[Federal Register Volume 64, Number 19 (Friday, January 29, 1999)]
[Rules and Regulations]
[Page 4535]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 99-55505]
=======================================================================
-----------------------------------------------------------------------
DEPARTMENT OF HEALTH AND HUMAN SERVICES
Food and Drug Administration
21 CFR Part 178
Indirect Food Additives: Adjuvants, Production Aids, and
Sanitizers
CFR Correction
In Title 21 of the Code of Federal Regulations, parts 170 to 199,
revised as of April 1, 1998, make the following corrections:
1. In Sec. 178.3130(b), on page 364, in the second column, in the
first line of number 2 under Alkyl mono- and disulfonic acids, correct
``be'' to read ``to'', and in the same column, at the end of the fourth
paragraph, after the words ``such foods have a pH'', add the words
``above 5.0''.
2. In Sec. 178.3620(c)(3), on page 384, in the first column, in the
first full paragraph, line 14, after the words ``Loosen the'' correct
``top'' to read ``topmost'' and add the following:
* * * * *
``few millimeters of each adsorbent layer with the end of a metal
rod before the addition of the next layer. Continue packing in this
manner until all the 14 grams of the adsorbent is added to the tube.
Level off the top of the adsorbent by pressing down firmly with a flat
glass rod or metal plunger to make the depth of the adsorbent bed
approximately 12.5 centimeters in depth. Turn off the vacuum and remove
the suction flask. Fit the 500-milliliter reservoir onto the top of the
chromatographic column and prewet the column by passing 100 milliliters
of isooctane through the column. Adjust the nitrogen pressure so that
the rate of descent of the isooctane coming off the column is between
2-3 milliliters per minute. Discontinue pressure just before the last
of the isooctane reaches the level of the adsorbent. (Caution: Do not
allow the liquid level to recede below the adsorbent level at any
time.) Remove the reservoir and decant the 5-milliliter isooctane
concentrate solution onto the column and with slight pressure again
allow the liquid level to recede to barely above the adsorbent level.
Rapidly complete the transfer similarly with two 5-milliliter portions
of isooctane, swirling the flask repeatedly each time to assure
adequate washing of the residue. Just before the final 5-milliliter
wash reaches the top of the adsorbent, add 100 milliliters of isooctane
to the reservoir and continue the percolation at the 2-3 milliliters
per minute rate. Just before the last of the isooctane reaches the
adsorbent level, add 100 milliliters of 10 percent benzene in isooctane
to the reservoir and continue the percolation at the''
* * * * *
2.In Sec. 178.3910(a)(2) table, on pages 406 and 407, in the first
column, under ``List of substances'', correct the second, third, and
fifth entries to read as follows:
* * * * *
-Butyl--hydroxypoly(oxypropyl-ene) (CAS Reg. No.
9003-13-8) having a minimum molecular weight of 1000.
-Lauroyl--hydroxpoly (oxyethylene) (CAS Reg. No.
9004-81-3) having a minimum molecular weight of 200.
* * * * *
alpha-Alkyl-omega-hydroxypoly-(oxyethylene) produced by the
condensation of 1 mole of C12-C15 straight chain
primary alcohols with an average of 3 moles of ethylene oxide (CAS Reg.
No. 68002-97-1).
* * * * *
[FR Doc. 99-55505 filed 1-28-99; 8:45 am]
BILLING CODE 1505-01-D
