[Federal Register Volume 64, Number 199 (Friday, October 15, 1999)]
[Notices]
[Pages 55943-55944]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 99-27025]
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DEPARTMENT OF HEALTH AND HUMAN SERVICES
Agency for Toxic Substances and Disease Registry
[ATSDR-152]
Availability of Draft Toxicological Profiles
AGENCY: Agency for Toxic Substances and Disease Registry (ATSDR),
Department of Health and Human Services (HHS).
ACTION: Notice of availability.
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SUMMARY: The Comprehensive Environmental Response, Compensation, and
Liability Act of 1980 (CERCLA), as amended by the Superfund Amendments
and Reauthorization Act of 1986 (SARA), section 104(i)(3) [42 U.S.C.
9604(i)(3)] directs the Administrator of ATSDR to prepare toxicological
profiles of priority hazardous substances and to revise and publish
each updated toxicological profile as necessary. This notice announces
the availability of the 13th set of toxicological profiles, which
consists of six updated drafts, prepared by ATSDR for review and
comment.
DATES: In order to be considered, comments on these draft toxicological
profiles must be received on or before February 22, 2000. Comments
received after the close of the public comment period will be
considered at the discretion of ATSDR based upon what is deemed to be
in the best interest of the general public.
ADDRESSES: Requests for copies of the draft toxicological profiles
should be sent to the attention of Ms. Loretta Norman, Division of
Toxicology, Agency for Toxic Substances and Disease Registry, Mailstop
E-29, 1600 Clifton Road, NE., Atlanta, Georgia 30333. Comments
regarding the draft toxicological profiles should be sent to the
attention of Dr. Ganga Choudhary, Division of Toxicology, Agency for
Toxic Substances and Disease Registry, Mailstop E-29, 1600 Clifton
Road, NE., Atlanta, Georgia 30333.
Requests for the draft toxicological profiles must be in writing,
and must specifically identify the hazardous substance(s) profile(s)
that you wish to receive. ATSDR reserves the right to provide only one
copy of each profile requested, free of charge. In case of extended
distribution delays, requestors will be notified.
Written comments and other data submitted in response to this
notice and the draft toxicological profiles should bear the docket
control number ATSDR-152. Send one copy of all comments and three
copies of all supporting documents to Dr. Ganga Choudhary at the above
stated address by the end of the comment period. Because all public
comments regarding ATSDR toxicological profiles are available for
public inspection, no confidential business or other confidential
information should be submitted in response to this notice.
FOR FURTHER INFORMATION CONTACT: Ms. Loretta Norman, Division of
Toxicology, Agency for Toxic Substances and Disease Registry, Mailstop
E-29, 1600 Clifton Road, NE., Atlanta, Georgia 30333, telephone (404)
639-6322.
SUPPLEMENTARY INFORMATION: The Superfund Amendments and Reauthorization
Act (SARA) (Pub. L. 99-499) amends the Comprehensive Environmental
Response, Compensation, and Liability Act (CERCLA or Superfund) (42
U.S.C. 9601 et seq.) by establishing certain responsibilities for the
ATSDR and the Environmental Protection Agency (EPA) with regard to
hazardous substances which are most commonly found at facilities on the
CERCLA National Priorities List (NPL). Among these responsibilities is
that the Administrator of ATSDR prepare toxicological profiles for
substances included on the priority lists of hazardous substances.
These lists identified 275 hazardous substances that ATSDR and EPA
determined pose the most significant potential threat to human health.
The availability of the revised priority list of 275 hazardous
substances was announced in the Federal Register on November 17, 1997
(62 FR 61332). For prior versions of the list of substances see Federal
Register notices dated April 17, 1987 (52 FR 12866); October 20, 1988
(53 FR 41280); October 26, 1989 (54 FR 43619); October 17, 1990 (55 FR
42067); October 17, 1991 (56 FR 52166); October 28, 1992 (57 FR 48801);
February 28, 1994 (59 FR 9486); and April 29, 1996 (61 FR 18744).
(CERCLA also requires ATSDR to assure the initiation of a research
program to fill data needs associated with the substances.)
Section 104(i)(3) of CERCLA (42 U.S.C. 9604(i)(3)) outlines the
content of these profiles. Each profile will include an examination,
summary and interpretation of available toxicological information and
epidemiologic evaluations. This information and these data are to be
used to identify the levels of significant human exposure for the
substance and the associated health effects. The profiles must also
include a determination of whether adequate information on the health
effects of each substance is available or in the process of
development. When adequate information is not available, ATSDR, in
cooperation with the National Toxicology Program (NTP), is required to
assure the initiation of research to determine these health effects.
Although key studies for each of the substances were considered
during the profile development process, this Federal Register notice
seeks to solicit any additional studies, particularly unpublished data
and ongoing studies, which will be evaluated for possible addition to
the profiles now or in the future.
The following draft toxicological profiles will be made available
to the public on or about October 17, 1999.
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Document Hazardous substance CAS No.
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1............................. ASBESTOS............. 001332-21-4
AMOSITE ASBESTOS..... 012172-73-5
CHRYSOTILE ASBESTOS.. 012001-29-5
2............................. BENZIDINE............ 000092-87-5
3............................. 1,2-DICHLOROETHANE... 000107-06-2
4............................. DI-N-BUTYL PHTHALATE. 000084-74-2
5............................. METHYL PARATHION..... 000298-00-0
6............................. PENTACHLOROPHENOL.... 000087-86-5
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[[Page 55944]]
All profiles issued as ``Drafts for Public Comment'' represent
ATSDR's best efforts to provide important toxicological information on
priority hazardous substances. We are seeking public comments and
additional information which may be used to supplement these profiles.
ATSDR remains committed to providing a public comment period for these
documents as a means to best serve public health and our clients.
Dated: October 8, 1999.
Georgi Jones,
Director, Office of Policy and External Affairs, Agency for Toxic
Substances and Disease Registry.
[FR Doc. 99-27025 Filed 10-14-99; 8:45 am]
BILLING CODE 4163-70-P
