[Federal Register Volume 60, Number 220 (Wednesday, November 15, 1995)]
[Notices]
[Pages 57451-57452]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 95-28209]
-----------------------------------------------------------------------
DEPARTMENT OF HEALTH AND HUMAN SERVICES
Public Health Service
National Toxicology Program (NTP) Board of Scientific Counselors'
Meeting; Review of Draft NTP Technical Reports
Pursuant to Public Law 92-463, notice is hereby given of the next
meeting of the NTP Board of Scientific Counselors Technical Reports
Review Subcommittee on December 5, 1995, in the Conference Center,
Building 101, South Campus, National Institute of Environmental Health
Sciences (NIEHS), 111 Alexander Drive, Research Triangle Park, North
Carolina. The meeting will begin at 8:30 a.m. and is open to the
public. The agenda topic is the peer review of draft Technical Reports
of long-term toxicology and carcinogenesis studies from the National
Toxicology Program.
Tentatively scheduled to be peer reviewed on December 5 are draft
Technical Reports of six two-year studies, listed alphabetically, along
with supporting information in the attached table. All studies were
done using Fischer 344 rats and B6C3F1 mice. The order of review
is given in the far right column of the table. Copies of the draft
Reports may be obtained, as available, from: Central Data Management,
MD A0-01, P.O. Box 12233, Research Triangle Park, NC 27709 (919/541-
3419).
Persons wanting to make a formal presentation regarding a
particular Technical Report must notify the Executive Secretary by
telephone, by FAX, or by mail no later than November 30, 1995, and
provide a written copy in advance of the meeting so copies can be made
and distributed to all Subcommittee members and staff and made
available at the meeting for attendees. Written statements should
supplement and may expand on the oral presentation. Oral presentations
should be limited to no more than five minutes.
The program would welcome receiving toxicology and carcinogenesis
information from completed, ongoing, or planned studies by others, as
well as current production data, human exposure information, and use
patterns for any of the chemicals listed in this announcement. Please
contact Central Data Management at the address given above, and they
will relay the information to the appropriate staff scientist.
The Executive Secretary, Dr. Larry G. Hart, P.O. Box 12233,
Research Triangle Park, North Carolina 27709 (telephone 919/541-3971;
FAX 919/541-0719) will furnish agenda and a roster of Subcommittee
members prior to the meeting. Summary minutes subsequent to the meeting
will be available upon request to Central Data Management.
Dated: November 3, 1995.
Kenneth Olden,
Director, National Toxicology Program.
Summary Data for Technical Reports Tentatively Scheduled for Review at the Meeting of the Board of Scientific
Counselors' Technical Reports Review Subcommittee
[December 5, 1995]
----------------------------------------------------------------------------------------------------------------
Technical Report Review
Chemical CAS No. No. Primary Uses Route/Exposure Levels Order
----------------------------------------------------------------------------------------------------------------
D & C Yellow No. 11, 8003-22-3.. TR-463 Color additive used in Dosed-Feed (NIH-07): 4
cosmetic and Rats: 0, 0.05, 0.17,
externally applied to OR 0.5%; 60/GROUP.
drugs. Contaminant of
D&C Yellow 10, a
compound which FDA is
currently considering
for approval for
contact lenses.
Molybdenum Trioxide, 1313-27-5.. TR-462 In manufacture of Inhalation (AIR): Rats 6
molybdenum metals; & Mice: 10, 30, OR 100
corrosion inhibitor; MG/M3; 50/SEX/SPECIES/
catalyst; chemical GROUP.
analysis reagent;
alloying agent in
steel; agricultural
chemical; component of
ceramics, enamel &
pigments.
[[Page 57452]]
Nitromethane, 75-52-5........... TR-461 Fuel additive and Inhalation (AIR): Rats: 5
propellant. Cellulosic 0, 94, 188, OR 375
compound solvent. PPM; 50/GROUP. Mice:
Intermediate for nitro 0,188, 375, OR 750
and amino alcohols. PPM; 50/GROUP.
Phenolphthalein, 77-09-8........ TR-465 Laboratory reagent. Dosed-Feed (NIH-07): 2
Dyes. Cathartic drug Rats: 0, 1.2, 2.5, OR
in laxatives. 5%; Mice 0, 0.3, 0.6,
OR 1.2% (50/SEX/
SPECIES/GROUP).
Sodium Xylene Sulfonate, 1300-72- TR-464 Hydrotrope in liquid Topical (ETHANOL): 3
7. detergents, shampoos, Rats: 0, 60, 120, OR
degreasing compounds. 240 MG/KG Mice: 0,
Used in textile, 182, 364, OR 727 MG/KG
paper, and leather (50/SEX/GROUP.
industries.
Tetrafluoroethylene, 116-14-3... TR-450 Monomer for Inhalation (AIR): Mice 1
polytetrafluoroethylen & Female Rats: 0, 312,
e polymers. 625, OR 1250; Male
Preparation of Rats: 0, 156, 312, OR
propellants for food 625 PPM; 50/GROUP.
product aerosols.
Chemical intermediate.
----------------------------------------------------------------------------------------------------------------
[FR Doc. 95-28209 Filed 11-14-95; 8:45 am]
BILLING CODE 4140-01-P-M
