00-29311. Availability of Final Toxicological Profiles

AGENCY:

Agency for Toxic Substances and Disease Registry (ATSDR), Department of Health and Human Services (HHS).

ACTION:

Notice of availability.

SUMMARY:

This notice announces the availability of one new final and six updated final toxicological profiles of priority hazardous substances comprising the twelfth set prepared by ATSDR.

FOR FURTHER INFORMATION CONTACT:

Ms. Franchetta Stephens, Division of Toxicology, Agency for Toxic Substances and Disease Registry, Mailstop E-29, 1600 Clifton Road, NE., Atlanta, Georgia 30333, telephone [phone] or [phone].

SUPPLEMENTARY INFORMATION:

The Superfund Amendments and Reauthorization Act (SARA) (Pub. L. 99-499) amends the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA or Superfund) (42 U.S.C. 9601 et seq.) by establishing certain requirements for ATSDR and the Environmental Protection Agency (EPA) with regard to hazardous substances which are most commonly found at facilities on the CERCLA National Priorities List (NPL). Among these statutory requirements is a mandate for the Administrator of ATSDR to prepare toxicological profiles for each substance included on the priority lists of hazardous substances. These lists identified 275 hazardous substances that ATSDR and EPA determined pose the most significant potential threat to human health. The availability of the revised list of the 275 most hazardous substances was announced in the Federal Register on October 21, 1999 (64 FR 56792). For prior versions of the list of substances see Federal Register notices dated November 17, 1997 (62 FR 61332); April 29, 1996 (61 FR 18744); April 17, 1987 (52 FR 12866); October 20, 1988 (53 FR 41280); October 26, 1989 (54 FR 43619); October 17, 1990 (55 FR 42067); October 17, 1991 (56 FR 52166); October 28, 1992 (57 FR 48801); and February 28, 1994 (59 FR 9486).

Notices (63 FR 56191) and (62 FR 55818) announcing the availability of the draft toxicological profiles for public review and comment were published in the Federal Register on October 21, 1998 or October 28, 1997 with notice of a 90-day public comment period for each profile, starting from the actual release date. Following the close of the comment period, chemical-specific comments were addressed, and where appropriate, changes were incorporated into each profile. The public comments and other data submitted in response to the Federal Register notices bear the docket control numbers ATSDR-137 or ATSDR-127. This material is available for public inspection at the Division of Toxicology, Agency for Toxic Substances and Disease Registry, Building 4, Suite 2400, Executive Park Drive, Atlanta, Georgia, (not a mailing address) between 8:00 a.m. and 4:30 p.m., Monday through Friday, except legal holidays.

Availability

This notice announces the availability of one new final and six updated final toxicological profiles comprising the twelfth set prepared by ATSDR. The following toxicological profiles are now available through the U.S. Department of Commerce, National Technical Information Service (NTIS), 5285 Port Royal Road, Springfield, Virginia 22161, telephone [phone]. There is a charge for these profiles as determined by NTIS.

Toxicological profile	NTIS order No.	CAS No.
Twelfth Set:
1. Arsenic	PB2000-108021	007440-38-2
2. Chromium	PB2000-108022	007440-47-3
3. Endosulfan	PB2000-108023	000115-29-7
Endosulfan, alpha		000959-98-8
Endosulfan, sulfate		001031-07-8
Endosulfan, beta		33213-65-9
4. Ethion	PB2000-108024	00563-12-2
5. Manganese	PB2000-108025	007439-96-5
Manganese chloride		007773-01-5
Manganese dioxide		001313-13-9
Maneb		012427-38-2
Methylcyclopentadienyl Manganese Tricarbony		012108-13-3
6. Methylene Chloride	PB2000-108026	000075-09-2
7. Toluene	PB2000-108028	000108-88-3

Dated: November 9, 2000.

Georgi Jones,

Director, Office of Policy and External Affairs, Agency for Toxic Substances and Disease Registry.