[Federal Register Volume 62, Number 245 (Monday, December 22, 1997)]
[Notices]
[Pages 66871-66876]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 97-33297]
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DEPARTMENT OF HEALTH AND HUMAN SERVICES
Centers for Disease Control and Prevention
[Number 816]
Individual Grants for Extramural Injury Research for Primary
Prevention of Unintentional Injuries, Acute Care, Disability
Prevention, and Biomechanics; Notice of Availability of Funds for
Fiscal Year 1998
Introduction
The Centers for Disease Control and Prevention (CDC) announces that
applications are being accepted for Injury Prevention and Control
Research Grants for fiscal year (FY) 1998.
CDC is committed to achieving the health promotion and disease
prevention objectives of Healthy People 2000, a national activity to
reduce morbidity and mortality and improve the quality of life. This
announcement is related to the priority area of Unintentional Injuries.
(To order a copy of Healthy People 2000, see the Section Where to
Obtain Additional Information.)
Authority
This program is authorized under Sections 301, 391-394 of the
Public Health Service Act (42 USC 241, 280b-280b-3), as amended.
Program regulations are set forth in Title 42 CFR Part 52.
Smoke-Free Workplace
CDC strongly encourages all grant and cooperative agreement
recipients to provide a smoke-free workplace and to promote the non-use
of all tobacco products, and Public Law 103-227, the Pro-Children Act
of 1994, prohibits smoking in certain facilities that receive Federal
funds in which education, library, day care, health care, and early
childhood development services are provided to children.
Eligible Applicants
Eligible applicants include all nonprofit and for-profit
organizations. Thus State and local health departments and State and
local governmental agencies, universities, colleges, research
institutions, and other public and private organizations, including
small, minority and/or woman-owned businesses are eligible for these
research grants. Current holders of CDC injury control research
projects are eligible to apply.
Note: An organization described in section 501(c)(4) of the
Internal Revenue Code of 1986 which engages in lobbying activities
shall not be eligible to receive Federal funds constituting an
award, a grant, contract, loan, or any other form.
Availability of Funds
Approximately $2.7 million is available for FY 1998 injury research
grants that include funding for projects that address primary
prevention of unintentional injuries (home and leisure, and motor
vehicle related-injuries), acute care, the prevention of secondary
conditions in persons with disabilities, and biomechanics.
Approximately $1,800,000 is available to support 6-8 projects that
address primary prevention of unintentional injuries (home and leisure,
and motor vehicle related-injuries), acute care, and the prevention of
secondary conditions in persons with disabilities. Awards will be made
for a 12-month budget period within a project period not to exceed
three years. The maximum funding level per year will not exceed
$300,000 (including both direct and indirect costs). Applications that
exceed the funding cap of $300,000 will be excluded from the
competition and returned to the applicant.
Approximately $900,000 is available to support 3-5 projects that
address
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biomechanics. Awards will be made for a 12-month budget period within a
project period not to exceed three years. The maximum funding level per
year will not exceed $300,000 (including both direct and indirect
costs). Applications that exceed the funding cap will be excluded from
the competition and returned to the applicant.
The specific program priorities for these funding opportunities are
outlined with examples in this announcement under the subheading,
``Programmatic Priorities.''
Continuation awards within the project period will be made based on
satisfactory progress demonstrated by investigators at work-in-progress
monitoring workshops (travel expenses for this annual one day meeting
should be included in the applicant's proposed budget), the achievement
of workplan milestones reflected in the continuation application, and
the availability of Federal funds. In addition, if funds are available,
continuation awards may be eligible for increased funding to offset
inflationary costs.
Use of Funds-Restrictions on Lobbying
Applicants should be aware of restrictions on the use of HHS funds
for lobbying of Federal or State legislative bodies. Under the
provisions of 31 U.S.C. 1352 (which has been in effect since December
23, 1989), recipients (and their subtier contractors) are prohibited
from using appropriated Federal funds (other than profits from a
Federal contract) for lobbying Congress or any Federal agency in
connection with the award of a particular contract, grant, cooperative
agreement, or loan. This includes grants/cooperative agreements that,
in whole or in part, involve conferences for which Federal funds cannot
be used directly or indirectly to encourage participants to lobby or to
instruct participants on how to lobby.
In addition, the current HHS Appropriations Act expressly prohibits
the use of appropriated funds for indirect or ``grass roots'' lobbying
efforts that are designed to support or defeat legislation pending
before State legislatures. Section 503 of the law provides as follows:
Section 503(a) No part of any appropriation contained in this
Act shall be used, other than for normal and recognized executive-
legislative relationships, for publicity or propaganda purposes, for
the preparation, distribution, or use of any kit, pamphlet, booklet,
publication, radio, television, or video presentation designed to
support or defeat legislation pending before the Congress or any
State legislature, except in presentation to the Congress or any
State legislature itself .
(b) No part of any appropriation contained in this Act shall be
used to pay the salary or expenses of any grant or contract
recipient, or agent acting for such recipient, related to any
activity designed to influence legislation or appropriations pending
before the Congress or any State legislature.
Prohibition on Use of CDC Funds for Certain Gun Control Activities
The Departments of Labor, Health and Human Services, and Education,
and Related Agencies Appropriations Act, 1998, specifies that: ``none
of the funds made available for injury prevention and control at the
Centers for Disease Control and Prevention may be used to advocate or
promote gun control.''
Anti-Lobbying Act requirements prohibit lobbying Congress with
appropriated Federal monies. Specifically, this Act prohibits the use
of Federal funds for direct or indirect communications intended or
designed to influence a Member of Congress with regard to specific
Federal legislation. This prohibition includes the funding and
assistance of public grassroots campaigns intended or designed to
influence Members of Congress with regard to specific legislation or
appropriation by Congress.
In addition to the restrictions in the Anti-Lobbying Act, CDC
interprets the language in the CDC's Appropriations Act to mean that
CDC's funds may not be spent on political action or other activities
designed to affect the passage of specific Federal, State, or local
legislation intended to restrict or control the purchase or use of
firearms.
Background and Definitions
A. Background
By nearly every measure, injury ranks as one of the nation's most
pressing health problems. More than 150,000 people die each year as a
result of motor vehicle crashes, falls, fires, drownings, poisonings,
suicides, homicides, and other types of injuries. Each year, 56 million
people sustain injuries severe enough to require medical treatment, and
for every 100 people injured, the effects are serious enough to require
162 days of restricted activity. Thirty-four million injured persons
visit emergency departments and another 2.7 million are hospitalized.
Injury is the leading cause of death for Americans between the ages
of one and 44 years, and the leading cause of potential years of life
lost. Young children are at the greatest risk from car crashes (both as
occupants and pedestrians), drownings, and fires. Adolescents and young
adults, especially males, are at highest risk of death from motor-
vehicle crashes and gunshot wounds. For people older than 75, falls are
the leading cause of death.
Although the greatest cost of injury is in human suffering and
loss, the financial cost of injury is estimated at more than $224
billion, an increase of 42 percent in the last decade. These costs
include direct medical care and rehabilitation costs as well as lost
wages of the individual and productivity losses to the nation.
Opportunities to understand and prevent unintentional injuries and
reduce their effects are available. Maximizing these opportunities for
prevention and control requires a broad approach which will incorporate
many disciplines that previously have not been an integral part of
public health efforts. Many of these opportunities and research
priorities are identified in Healthy People 2000; Injury in America
(National Academy Press, 2101 Constitution Avenue, NW, Washington, D.C.
20418--ISBN0-309-03545-7); Injury Prevention: Meeting the Challenge
(supplement to the American Journal of Preventive Medicine, (Vol. 5,
no. 3, 1989); and Cost of Injury (Dorothy P. Rice, Ellen J. MacKenzie,
and Associates, Cost of Injury: A Report to the Congress, San
Francisco, California: Institute for Health and Aging, University of
California and Injury Prevention Research Center, The Johns Hopkins
University, 1989).
B. Definitions
1. Injury is defined as physical damage to an individual that
occurs over a short period of time as a result of acute exposure to one
of the forms of physical energy in the environment or to chemical
agents or the acute lack of oxygen. The three phases of injury control
are defined as prevention, acute care, and rehabilitation. Within these
phases the major categories of injury are intentional, unintentional,
and occupational. Intentional injuries result from interpersonal or
self-inflicted violence, and include homicide, assaults, suicide and
suicide attempts, elder and child abuse, violence against women, and
sexual assault. Unintentional or unintended injuries include those that
result from motor vehicle collisions, falls, fires, poisonings, and
drownings. Occupational injuries occur at the worksite and include
unintentional trauma such as work-related motor-vehicle injuries,
drownings, electrocutions, and intentional injuries in the workplace
such as homicide. Not included in this definition of occupational
injuries are cumulative
[[Page 66873]]
trauma disorders, back injuries not caused by acute trauma, and effects
of repeated exposures to chemical or physical agents.
2. Individual injury control research projects (R01) are defined as
research designed to:
a. Elucidate the chain of causation--the etiology and mechanisms--
of injuries and subsequent disabilities; or
b. Yield results directly applicable to identifying interventions
to prevent injury occurrence or minimize disability; or
c. Evaluate the effect of known interventions on injury morbidity,
mortality, disability, and costs.
Purpose
The purposes of this program are to:
A. Support injury prevention and control research on priority
issues as delineated in Healthy People 2000; Injury in America; Injury
Prevention: Meeting the Challenge; and Cost of Injury.
B. Encourage professionals from a wide spectrum of disciplines such
as engineering, medicine, health care, public health, behavioral and
social sciences, and others, to undertake research to prevent and
control injuries.
C. Expand the development and evaluation of current or new
intervention methods and strategies for preventing unintentional
injuries.
D. Build the scientific base for the prevention of unintentional
injuries and deaths.
Program Requirements
The following are applicant requirements:
A. A principal investigator who has conducted research, published
the findings in peer-reviewed journals, and has specific authority and
responsibility to carry out the proposed project.
B. Demonstrated experience (on the applicant's project team) in
conducting, evaluating, and publishing in peer-reviewed journals injury
control research (as previously defined).
C. Effective and well-defined working relationships within the
performing organization and with outside entities that will ensure
implementation of the proposed activities.
D. The ability to carry out an injury control research project as
previously defined under Background and Definitions, (B.2.a-c).
E. The overall match between the applicant's proposed theme and
research objectives and the program priorities as described under the
heading ``Programmatic Priorities.''
Note: Grant funds will not be made available to support the
provision of direct care services. Eligible applicants may enter
into contracts, including consortia agreements (as set forth in the
PHS Grants Policy Statement) as necessary to meet the requirements
of the program and strengthen the overall application.
Programmatic Priorities
Grant applications for research projects that address primary
prevention of unintentional injuries (home and leisure, and motor
vehicle related-injuries ), acute care, the prevention of secondary
conditions in persons with injury-related disabilities, and
biomechanics are sought. The focus of grants should reflect the broad-
based need to control injury morbidity, mortality, disability, and
costs.
Applications must address a programmatic priority area as noted
below. Examples of possible projects listed under the priority areas
below are not exhaustive. Innovative alternative approaches are
encouraged.
For primary prevention of unintentional injuries, there is
programmatic interest in the areas of home and leisure, and motor
vehicle injuries:
(1) Specifically, there is special programmatic interest in the
development and evaluation of unintentional injury prevention
strategies that can be applied in inpatient and outpatient clinical
and/or managed care settings (e.g., HMOs, PPOs, clinics, clinicians'
offices, academic health centers, etc.). For example, health care-based
programs that reduce the injury risk to elderly drivers with medical
conditions, fall prevention programs among the elderly, and other
methods of delivering injury prevention through clinical practice or
managed care settings, are acceptable.
(2) There is interest in applying behavioral research to injury
prevention science. That is, the application of behavior change
strategies to injury problems. For example, applying ``stages-of-
change'' or the transtheoretical model to modify behaviors that will
increase the protection of motor vehicle occupants, testing peer-to-
peer and cross-generational counseling approaches, applying elements of
social learning theory or social cognitive theory to changing
unintentional injury risk behaviors, or implementing interventions that
take advantage of several theoretical approaches simultaneously are
acceptable.
(3) There is programmatic interest in research that evaluates the
effects of making low-cost safety devices more available and or
accessible to special and general populations. There is interest, as
well, in the use of economic incentive systems, such as discounts and
rebates, or through insurance programs (health, automobile or life).
For example, these approaches could be studied as methods for
increasing the use and maintenance of residential smoke detectors or
sprinkler systems in high risk or rural neighborhoods, or to promote
bicycle helmet ownership and use at the community level.
Community based research is particularly relevant, and studies that
replicate successful programs in new settings or with other populations
are eligible.
Unintentional injury prevention proposals primarily addressing the
epidemiology of unintentional injuries will not be funded under this
announcement.
A more thorough discussion of methodologies for conducting
prevention effectiveness research is presented in ``A Framework for
Assessing the Effectiveness of Disease and Injury Prevention,'' (CDC
Morbidity and Mortality Weekly Report, March 27, 1992, Volume 41,
Number RR-3, pp. 5-11) and in ``Assessing the Effectiveness of Disease
and Injury Prevention Programs: Costs and Consequences'\5\ (CDC
Morbidity and Mortality Weekly Report, August 18, 1995, Vol. 44, No.
RR10). To receive information on these reports see the section Where to
Obtain Additional Information.
In acute care there is programmatic interest in intensifying the
role of the hospital emergency department and inpatient hospital trauma
services in public health surveillance (e.g., emergency department
surveillance systems, inpatient trauma registries), clinical prevention
services (e.g., protocols, interventions, and referrals for patients
injured in interpersonal violence or identified as alcohol drinkers who
drink at a hazardous level), evaluation of acute care effectiveness and
costs (e.g., studies of trauma care systems in terms of their impact on
morbidity and disability, assessments of treatment modalities that are
used conventionally or are emerging rapidly in mainstream clinical
practice).
(1) There is interest in establishing electronic linkages and
common data elements across clinical information and public health
surveillance systems (e.g., incorporating NCIPC's Data Elements for
Emergency Department Systems, Release 1.0 in distributed record
systems) to facilitate reporting of injury incidence and outcome data.
There is interest in developing or further refining measures of injury
severity (e.g., indices that stratify injuries by anatomic severity to
facilitate evaluation of
[[Page 66874]]
trauma care processes and outcomes. Acute care-based, public health
surveillance systems are most valuable where they provide comprehensive
coverage of defined populations, are used to identify injury causes,
risk factors, treatments and outcomes, and lend themselves to
developing or refining clinical and epidemiologic measures of injuries
including their severity and costs. Information on obtaining Data
Elements for Emergency Department Systems, Release 1.0, can be found
under the section Where to Obtain Additional Information.
(2) There is interest in evaluating the effectiveness and costs of
programs that identify patients at high risk for subsequent injury and
provide on-site interventions or referrals to further define the role
of clinical prevention services in acute care settings. There is
interest in research that evaluates ways to overcome barriers to
service provision in emergency departments and inpatient trauma
services to encourage greater use of clinical prevention services shown
to be effective and economical. Acute care practitioners are uniquely
positioned to help reduce or eliminate injury risk factors in the
patient populations they serve. In emergency departments and inpatient
trauma services there are opportunities to introduce or extend clinical
prevention services (e.g., screening and brief intervention for
patients with mild to moderate alcohol problems and identification and
referral of patients with severe alcohol problems to specialized
alcohol treatment services).
(3) There is interest in comprehensive evaluations of the
effectiveness of trauma care systems (e.g., baseline and follow-up
study of State or regional trauma care systems that identifies the
system's impact on special populations such as children and the elderly
as well as overall system effectiveness). There is interest in
systematic studies in people of standard ways of delivering acute care
as well as new interventions, particularly where key questions persist
about benefits, risks, and costs (e.g., clinical trials of procedures,
medications, or protocols used in trauma care). Systematic,
empirically-based studies of effectiveness and costs are needed to
evaluate poison control systems, trauma care systems, and specific
diagnostic and therapeutic interventions currently used or rapidly
emerging in acute care of injured persons.
In disability prevention, there is programmatic interest in
community-based research to prevent the occurrence and reduce the
severity of disabilities or other adverse outcomes among persons with
traumatic brain injury (TBI) and spinal cord injury (SCI). Adverse
outcomes include secondary conditions such as pressure ulcers and
contractures; cognitive, behavioral, or psychological disorders; and
other definable conditions associated with TBI or SCI. Research topics
relating to TBI or SCI must include any of the following:
(1) Identifying risk factors associated with adverse outcomes
following rehabilitation.
(2) Developing or evaluating interventions that are delivered in
the community setting or as part of outpatient rehabilitation care to
prevent or minimize the impact of adverse outcomes or secondary
conditions.
(3) Defining the incidence of and adverse outcomes associated with
mild TBI (i.e., nonfatal TBI not resulting in hospitalization) in a
defined geopolitical population. Research proposals may address all age
groups or may be limited to children and adolescents. Alcohol and drug
use or dependence can be among a range of outcomes considered, but
should not be the primary focus of the project.
(4) Defining patterns of post acute care among persons with SCI or
TBI resulting in hospitalization, using population-based data. The
evolving nature of health care delivery may have changed the
availability of rehabilitation, the location where rehabilitative
services are delivered, the timing of services received, and the length
of the rehabilitation period. Research in this area should define the
type of facility where rehabilitation services are received, timing of
rehabilitation service delivery, length of rehabilitation period, and
payment source for services.
Disability prevention proposals primarily addressing alcohol and
other drug use or dependence will not be funded under this
announcement.
In biomechanics, there is programmatic interest in traumatic brain
and spinal cord injury (TBI/SCI). This interest includes the
biomechanical evaluation of intervention concepts and strategies (e.g.,
multi-use recreational helmets, mouth and face protection devices for
athletes, energy-absorbing playground surfaces, hip pads, motor vehicle
side impact and rollover countermeasures, etc.). There is special
interest in defining human tolerance limits for injury among very young
children, women, and older persons; the development of biofidelic
models to elucidate injury physiology and pharmacologic, surgical,
rehabilitation, and other interventions; improvements in injury
assessment technology; understanding impact injury mechanisms; and
quantifying injury-related biomechanical responses for critical areas
of the human body (e.g., brain and vertebral injury with spinal cord
involvement). Consideration will also be given to the biomechanics of
thoracic and abdominal viscera, musculature and joints including the
articular cartilage, tendons and ligaments.
Reporting Requirements
An original and two copies of the financial status and progress
reports are due 90 days after the end of each budget period. Final
financial status and progress reports are due 90 days after the end of
the project period.
Application Content
Applications for injury control research grants should include:
A. The project's focus that justifies the research needs and
describes the scientific basis for the research, the expected outcome,
and the relevance of the findings to reduce injury morbidity,
mortality, disability, and economic losses. This focus should be based
on recommendations in Healthy People 2000; Injury In America; Injury
Prevention: Meeting the Challenge; and Cost of Injury and should seek
creative approaches that will contribute to a national program for
injury control.
B. Specific, measurable, and time-framed objectives.
C. A detailed plan describing the methods by which the objectives
will be achieved, including their sequence. A comprehensive evaluation
plan is an essential component of the application.
D. A description of the grant's principal investigator's role and
responsibilities.
E. A description of all the project staff regardless of their
funding source. It should include their title, qualifications,
experience, percentage of time each will devote to the project, as well
as that portion of their salary to be paid by the grant.
F. A description of those activities related to, but not supported
by the grant.
G. A description of the involvement of other entities that will
relate to the proposed project, if applicable. It should include
commitments of support and a clear statement of their roles.
H. A detailed first year's budget for the grant with future annual
projections, if relevant. Awards will be made for project periods of up
to three years.
I. Applicants must identify the principal injury phase (prevention,
acute care, rehabilitation) discipline
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(biomechanics, epidemiology) or type of injury (intentional,
unintentional) upon which their project focuses.
An applicant organization has the option of having specific salary
and fringe benefit amounts for individuals omitted from the copies of
the application which are made available to outside reviewing groups.
To exercise this option: on the original and five copies of the
application, the applicant must use asterisks to indicate those
individuals for whom salaries and fringe benefits are not shown; the
subtotals must still be shown. In addition, the applicant must submit
an additional copy of page four of Form PHS-398, completed in full,
with the salary and fringe amounts shown. This budget page will be
reserved for internal staff use only.
Evaluation Criteria
Upon receipt, applications will be reviewed by CDC staff for
completeness and responsiveness as outlined under the previous heading,
Program Requirements (A-E). Incomplete applications and applications
that are not responsive will be returned to the applicant without
further consideration. Applications that are complete and responsive
may be subjected to a preliminary evaluation by a peer review group to
determine if the application is of sufficient technical and scientific
merit to warrant further review (triage); the CDC will withdraw from
further consideration applications judged to be noncompetitive and
promptly notify the principal investigator/program director and the
official signing for the applicant organization. Those applications
judged to be competitive will be further evaluated by a dual review
process. Awards will be made based on priority score ranking by the
Injury Research Grants Review Committee (IRGRC), programmatic
priorities and needs as determined by the Advisory Committee for Injury
Prevention and Control, and the availability of funds.
A. The first review will be a peer review conducted by the IRGRC on
all applications. Factors to be considered will include:
1. The specific aims of the research project, i.e., the broad long-
term objectives, the intended accomplishment of the specific research
proposal, and the hypothesis to be tested.
2. The background of the proposal, i.e., the basis for the present
proposal, the critical evaluation of existing knowledge, and specific
identification of the injury control knowledge gaps which the proposal
is intended to fill.
3. The significance and originality from a scientific or technical
standpoint of the specific aims of the proposed research, including the
adequacy of the theoretical and conceptual framework for the research.
4. For competitive renewal applications, the progress made during
the prior project period. For new applications, (optional) the progress
of preliminary studies pertinent to the application.
5. The adequacy of the proposed research design, approaches, and
methodology to carry out the research, including quality assurance
procedures, plan for data management, and statistical analysis plan.
6. The extent to which the research findings will lead to feasible,
cost-effective injury interventions.
7. The extent to which the evaluation plan will allow the
measurement of progress toward the achievement of the stated
objectives.
8. Qualifications, adequacy, and appropriateness of personnel to
accomplish the proposed activities.
9. The degree of commitment and cooperation of other interested
parties (as evidenced by letters detailing the nature and extent of the
involvement).
10. The reasonableness of the proposed budget to the proposed
research and demonstration program.
11. Adequacy of existing and proposed facilities and resources.
B. The second review will be conducted by the Advisory Committee
for Injury Prevention and Control. The factors to be considered will
include:
1. The results of the peer review.
2. The significance of the proposed activities in relation to the
priorities and objectives stated in Healthy People 2000; Injury in
America; Injury Prevention; Meeting the Challenge; and Cost of Injury.
3. National needs.
4. Program balance among the three phases of injury control:
prevention, acute care, and rehabilitation; the major disciplines of
injury control: biomechanics and epidemiology; target populations
(e.g., adolescents, children, racial and ethnic minorities, rural
residents, farm families, and people with low incomes); and
5. Budgetary considerations.
C. Continued Funding:
Continuation awards made after FY 1998, but within the project
period, will be made on the basis of the availability of funds and the
following criteria:
1. The accomplishments reflected in the progress report of the
continuation application indicate that the applicant is meeting
previously stated objectives or milestones contained in the project's
annual workplan and satisfactory progress demonstrated through
presentations at work-in-progress monitoring workshops.
2. The objectives for the new budget period are realistic,
specific, and measurable.
3. The methods described will clearly lead to achievement of these
objectives.
4. The evaluation plan will allow management to monitor whether the
methods are effective.
5. The budget request is clearly explained, adequately justified,
reasonable and consistent with the intended use of grant funds.
Executive Order 12372 Review
Applications are not subject to the review requirements of
Executive Order 12372.
Public Health System Reporting Requirement
This program is not subject to the Public Health System Reporting
Requirements.
Catalog of Federal Domestic Assistance Number
The Catalog of Federal Domestic Assistance number is 93.136.
Other Requirements
A. Human Subjects
If the proposed project involves research on human subjects, the
applicant must comply with the Department of Health and Human Services
Regulations, 45 CFR Part 46, regarding the protection of human
subjects. Assurance must be provided to demonstrate that the project
will be subject to initial and continuing review by an appropriate
institutional review committee. The applicant will be responsible for
providing assurance in accordance with the appropriate guidelines and
forms provided in the application kit.
B. Animal Subjects
If the proposed project involves research on animal subjects, the
applicant must comply with the ``PHS Policy on Humane Care and Use of
Laboratory Animals by Awardee Institutions.'' An applicant organization
proposing to use vertebrate animals in PHS-supported activities must
file an Animal Welfare Assurance with the Office for Protection from
Research Risks at the National Institutes of Health.
C. Women, Racial and Ethnic Minorities
It is the policy of the CDC to ensure that women and racial and
ethnic groups will be included in CDC
[[Page 66876]]
supported research projects involving human subjects, whenever feasible
and appropriate. Racial and ethnic groups are those defined in OMB
Directive No. 15 and include American Indian or Alaska Native, Asian,
Black or African American, Hispanic or Latino, Native Hawaiian or other
Pacific Islander. Applicants shall ensure that women, racial and ethnic
minority populations are appropriately represented in applications for
research involving human subjects. Where clear and compelling rationale
exist that inclusion is inappropriate or not feasible, this situation
must be explained as part of the application.
In conducting the review of applications for scientific merit,
review groups will evaluate proposed plans for inclusion of minorities
and both sexes as part of the scientific assessment and assigned score.
This policy does not apply to research studies when the investigator
cannot control the race, ethnicity and/or sex of subjects. Further
guidance to this policy is contained in the Federal Register, Vol. 60,
No. 179, Friday, September 15, 1995, pages 47947-47951.
D. Paperwork Reduction Act
Projects that involve the collection of information from 10 or more
individuals and funded by this grant program will be subject to review
by the Office of Management and Budget (OMB) under the Paperwork
Reduction Act.
Application Submission and Deadlines
A. Preapplication Letter of Intent
Although not a prerequisite of application, a non-binding letter of
intent-to-apply is requested from potential applicants. The letter
should be submitted to the Grants Management Specialist (whose address
is reflected in section B, ``Applications''). It should be postmarked
no later than two months prior to the planned submission deadline,
(e.g., January 26 for February 25 submission). The letter should
identify the announcement number, name the principal investigator, and
specify the injury phase or discipline addressed by the proposed
project. The letter of intent does not influence review or funding
decisions, but it will enable CDC to plan the review more efficiently,
and will ensure that each applicant receives timely and relevant
information prior to application submission.
B. Applications
Applicants should use Form PHS-398 and adhere to the ERRATA
Instruction Sheet for Form PHS-398 contained in the Grant Application
Kit. Please submit an original and five copies on or before February
25, 1998 to: Lisa G. Tamaroff, Grants Management Specialist, Grants
Management Branch, Procurement and Grants Office, Centers for Disease
Control and Prevention (CDC), 255 East Paces Ferry Road, NE., Room 300,
Atlanta, GA 30305.
C. Deadlines
1. Applications shall be considered as meeting the deadline if they
are either:
A. Received at the above address on or before the deadline date, or
B. Sent on or before the deadline date to the above address, and
are received in time for the review process. Applicants should request
a legibly dated U.S. Postal Service postmark or obtain a legibly dated
receipt from a commercial carrier or the U.S. Postal Service. Private
metered postmarks shall not be acceptable as proof of timely mailings.
2. Applications that do not meet the criteria above are considered
late applications and will be returned to the applicant.
Where To Obtain Additional Information
Application Packet
To receive additional written information call 1-888-GRANTS4. You
will be asked to leave your name, address, and phone number and will
need to refer to Announcement #816. CDC will not send application kits
by facsimile or express mail. Please refer to Announcement #816 when
requesting information and submitting an application.
Internet
This and other CDC announcements are also available through the CDC
homepage on the Internet. The address for the CDC homepage is [http://
www.cdc.gov]. For your convenience, you may be able to retrieve a copy
of the PHS Form 398 from [http://www.nih.gov80/grants/funding].
Business Management Technical Information
If you need further assistance after reviewing the contents of the
documents business management information may be obtained from Lisa
Tamaroff, Grants Management Specialist, Procurement and Grants Office,
Centers for Disease Control and Prevention (CDC), 255 East Paces Ferry
Road, NE., Mailstop E-13, Atlanta, GA 30305, telephone (404) 842-6796
or Internet:lgt1@cdc.gov.
Programmatic Technical Assistance
If you have programmatic question you may obtain information from
Ted Jones, Program Manager, Extramural Research Grants Branch, National
Center for Injury Prevention and Control, Centers for Disease Control
and Prevention (CDC), Mailstop K-58, 4770 Buford Highway, NE., Atlanta,
GA 30341-3724, telephone (770) 488-4824, Internet: tmj1@cdc.gov.
Potential applicants may obtain a copy of Healthy People 2000 (Full
Report, Stock No. 017-001-00474-0) or Healthy People 2000 (Summary
Report, Stock No. 017-001-00473-1) through the Superintendent of
Documents, Government Printing Office, Washington, DC 20402-9325,
telephone (202) 512-1800.
The document, ``Data Elements for Emergency Department System,
Release 1.0'', and subsequent revisions can be found at the National
Center for Injury Prevention and Control Web site: http://www.cdc.gov/
ncipc/pub-res/deedspage.htm.
Information for obtaining copies of Injury in America (National
Academy Press, 2101 Constitution Avenue, NW, Washington, DC 20418--
ISBN0-309-03545-7); Injury Prevention: Meeting the Challenge
(supplement to the American Journal of Preventive Medicine, (Vol. 5,
no. 3, 1989); Cost of Injury (Dorothy P. Rice, Ellen J. MacKenzie, and
Associates, Cost of Injury: A Report to the Congress, San Francisco,
California: Institute for Health and Aging, University of California
and Injury Prevention Research Center, The Johns Hopkins University,
1989); A Framework for Assessing the Effectiveness of Disease and
Injury Prevention,'' (CDC Morbidity and Mortality Weekly Report, March
27, 1992, Volume 41, Number RR-3, pp. 5-11); and in ``Assessing the
Effectiveness of Disease and Injury Prevention Programs: Costs and
Consequences'' (CDC Morbidity and Mortality Weekly Report, August 18,
1995, Vol. 44, No. RR10) is included on a separate sheet with the
application kit.
Dated: December 16, 1997.
Joseph R. Carter,
Acting Associate Director, Management and Operations, Centers for
Disease Control and Prevention (CDC).
[FR Doc. 97-33297 Filed 12-19-97; 8:45 am]
BILLING CODE 4160-18-U
