94-7349. Findings of Scientific Misconduct

[Federal Register Volume 59, Number 60 (Tuesday, March 29, 1994)]
[Unknown Section]
[Page 0]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 94-7349]


[[Page Unknown]]

[Federal Register: March 29, 1994]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

Office of the Secretary

 

Findings of Scientific Misconduct

AGENCY: Office of Secretary, HHS.

ACTION: Notice.

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SUMMARY: Notice is hereby given that on February 25, 1994, a Research 
Integrity Adjudications Panel of the Department Appeals Board issued a 
ruling upholding scientific misconduct findings of the Office of 
Research Integrity (ORI) in the following case:

    John C. Hiserodit, M.D.: An inquiry conducted by the University of 
Pittsburgh and an investigation conducted by the Office of Research 
Integrity found that Dr. Hiserodt deliberately and knowingly falsified 
four figures and one table to two research grant applications submitted 
to the National Institutes of Health, and deliberately and knowingly 
fabricated a laboratory notebook to cover up the falsifications in the 
grant applications. In reporting research results on antigen 
recognition by natural killer cells, Dr. Hiserodt falsely reported that 
a purportedly unique protein had a molecular weight of 48 kilodaltons 
by altering photographs of autoradiograms, falsely reported that this 
protein has been found in human cells, falsely reported the results of 
a gene sequence in response to questions raised by NIH grant reviewers 
about his experimental findings, and fabricated a laboratory notebook 
to cover-up the falsified research when questions about it were raised 
by investigating officials. Dr. Hiserodt has been debarred from 
receiving Federal grant or contract funds for a period of five years 
beginning March 9, 1984. In addition, any institution receiving PHS 
research support involving Dr. Hiserodt must monitor the accuracy of 
his research for an additional two-year period following the five-year 
debarment (for a total period of seven years) beginning March 9, 1999. 
He has also been prohibited from serving on PHS Advisory Committees or 
review groups for seven years beginning February 25, 1994. Dr. Hiserodt 
is also required to request correction of the article ``The Expression 
and Functional Involvement of Laminin-like Molecules in Non-MHC 
Restricted Cytotoxicity by Human Leu-19+/CD3-Natural Killer 
Lymphocytes,'' Journal of Immounology, Vol. 141, 3318-23, 19898, to 
indicate that Figure 2 in the article may not be relied upon.

FOR FURTHER INFORMATION CONTACT: Director, Division of Research 
Investigations, Office of Research Integrity, 301-433-5330.
Lyle W. Bivens,
Director, Office of Research Integrity.
[FR Doc. 94-7349 Filed 3-28-94; 8:45 am]
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