[Federal Register Volume 61, Number 64 (Tuesday, April 2, 1996)]
[Notices]
[Page 14563]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 96-7893]
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DEPARTMENT OF DEFENSE
Availability of Non-Exclusive, Exclusive, or Partially Exclusive
Licensing of U.S. Patent Application Concerning A Dengue Virus Vaccine
AGENCY: U.S. Army Medical Research and Materiel Command, DOD.
ACTION: Notice.
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SUMMARY: In accordance with 37 CFR 404.6, announcement is made of the
availability of U.S. Patent Application Serial No. 08/423,338 entitled
``Inactivated Dengue Virus Vaccine'', and filed April 17, 1995, for
licensing. This patent has been assigned to the United States
Government as represented by the Secretary of the Army.
ADDRESSES: Commander, U.S. Army Medical Research and Materiel Command,
ATTN: Staff Judge Advocate, Fort Detrick, Frederick, Maryland 21702-
5012.
FOR FURTHER INFORMATION CONTACT: Mr. John F. Moran, Patent Attorney,
(301) 619-2065 or telefax (301) 619-7714.
SUPPLEMENTARY INFORMATION: The invention describes an inactivated viral
vaccine designed to immunize and protect against disease caused by
dengue (DEN) viruses, including serotypes one, two, three, and four,
i.e. DEN-1, DEN-2, DEN-3, and DEN-4; it also describes a process to
produce the vaccine. The process consists of methods to replicate DEN
viruses to high titer in a suitable cell substrate, to purify the
viruses, and to inactivate them with formalin while maintaining their
antigenicity and immunogencity. The vaccine is designed for
administration by subcutaneous, intramuscular, or other suitable routes
with or without an adjuvant.
Gregory D. Showalter,
Army Federal Register Liaison Officer.
[FR Doc. 96-7893 Filed 4-1-96; 8:45 am]
BILLING CODE 3710-08-M
