98-10988. Availability for Non-Exclusive, Exclusive, or Partially Exclusive Licensing of U.S. Patent Applications Concerning CS6 Antigens Methods for Production of Antigens

[Federal Register Volume 63, Number 79 (Friday, April 24, 1998)]
[Notices]
[Page 20387]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 98-10988]



[[Page 20387]]

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DEPARTMENT OF DEFENSE

Department of the Army


Availability for Non-Exclusive, Exclusive, or Partially Exclusive 
Licensing of U.S. Patent Applications Concerning CS6 Antigens Methods 
for Production of Antigens

AGENCY: U.S. Army Medical Research and Materiel Command, DoD.

ACTION: Notice.

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SUMMARY: In accordance with 37 CFR 404.6, announcement is made of the 
availability of U.S. Patent Number 5,698,416 (entitled ``Methods for 
Production of Antigens Under Control of Temperature-Regulated Promotors 
in Enteric Bacteria'' and issued December 16, 1997) and U.S. Patent 
Application SN 08/799,145 (entitled ``Transformed Bacterial Containing 
CS6 Antigens and Vaccines'' filed May 13, 1994) for licensing. These 
inventions have been assigned to the United States Government as 
represented by the Secretary of the Army.

ADDRESSES: Commander, U.S. Army Medical Research and Materiel Command, 
Attn: Staff Judge Advocate, Fort Detrick, Frederick, Maryland 21702-
5012.

FOR FURTHER INFORMATION CONTACT: Mr. Charles Harris, Patent Attorney, 
[phone] or telefax [phone].

SUPPLEMENTARY INFORMATION: The inventions are related to (1) a CS6 
antigen for use in vaccines to protect from pathological effects of 
entertoxigenic E. coli and (2) method(s) for the preparation of 
proteins, and in particular a method which has been found to be 
especially useful for the preparation of antigens in E. coli. The 
natural and recombinant constructs giving rise to the proteins contain 
temperature-regulated promotors. The methods of the invention are 
exemplified by the production of antigens classified as colonization 
factor antigens (CFA) which have use as vaccines and for giving rise to 
antibodies for laboratory testing of antigens.
Gregory D. Showalter,
Army Federal Register Liaison Officer.
[FR Doc. 98-10988 Filed 4-23-98; 8:45 am]
BILLING CODE 3710-08-M