[Federal Register Volume 60, Number 85 (Wednesday, May 3, 1995)]
[Notices]
[Pages 21813-21814]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 95-10865]
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ENVIRONMENTAL PROTECTION AGENCY
[OPP-00408; FRL-4952-9]
Metabolism Testing Guideline; Notice of Workshop
AGENCY: Environmental Protection Agency (EPA).
ACTION: Notice of workshop.
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SUMMARY: There will be a 1-day workshop sponsored by the EPA's Office
of Pesticide Programs, to discuss the revision of the Metabolism
Testing Guideline.
DATES: The workshop will be held on Wednesday, May 24, 1995, from 8:30
a.m. to 5 p.m. Written comments must be submitted by May 17, 1995.
ADDRESSES: The workshop will be held at: Crystal Gateway Marriott, 1700
Jefferson Davis Highway, Arlington, VA. Interested persons are invited
to submit written comments in triplicate to: By mail: Public Response
and Program Resources Branch, Field Operations Division (7506C),
Environmental Protection Agency, 401 M St., SW., Washington, DC 20460.
In person, bring comments to: Rm. 1132, Crystal Mall #2, 1921 Jefferson
Davis Highway, Arlington, VA.
Comments and data may also be submitted electronically by sending
electronic mail (e-mail) to: opp-docket@epamail.epa.gov. Electronic
comments must be submitted as an ASCII file avoiding the use of special
characters and any form of encryption. Comments and data will also be
accepted on disks in WordPerfect in 5.1 file format or ASCII file
format. All comments and data in electronic form must be identified by
the docket number ``OPP-00408.'' No Confidential Business Information
(CBI) should be submitted through e-mail. Electronic comments on this
document may be filed online at many Federal Depository Libraries.
Additional information on electronic submissions can be found under the
SUPPLEMENTARY INFORMATION unit of this document.
FOR FURTHER INFORMATION CONTACT: By mail: Yiannakis M. Ioannou (7509C),
Office of Pesticide Programs, Environmental Protection Agency, 401 M
St., SW., Washington, DC 20460. Office location and telephone number:
Rm. 820D, CM #2, 192l Jefferson Davis Highway, Arlington, VA, (703)
305-7894. Copies of documents may be obtained by contacting: By mail:
Public Docket and Freedom of Information Section, Field Operations
Division (7506C), Office of Pesticide Programs, Environmental
Protection Agency, 40l M St., SW., Washington, DC 20460. Office
location and telephone number: Rm. ll28 Bay, CM #2, l92l Jefferson
Davis Highway, Arlington, VA, (703) 305-5805 or 5454.
SUPPLEMENTARY INFORMATION: The Pesticide Assessment Guidelines
Subdivision F, describe protocols for performing toxicology and related
tests to support registration of pesticides under the Federal
Insecticide, Fungicide, and Rodenticide Act (FIFRA). Some of the tests
are also used in tolerance reviews under the Federal Food, Drug, and
Cosmetic Act (FFDCA). Subdivision F was proposed for public comment in
1978 and published in October 1982. At that time, the Agency published
the criteria for performing a general metabolism study on a pesticide
and reserved a line item, Section 85-1, for a guideline on General
Metabolism Studies of Pesticides. The Toxic Substances Control Act
(TSCA) also specifies that General Metabolism studies can be required
under the TSCA section 4 test rule.
The proposed revisions are the result of efforts by Agency
scientists to improve the existing guideline to reflect current state-
of-the-art regarding metabolism of pesticides and other toxic
compounds. In addition, a need for revision was indicated by the
results of the Pesticide Reregistration Rejection Rate Analysis as well
as by comments received in response to the notice published in the
Federal Register of September 19, 1990 (55 FR 38578).
The agenda for the meeting and a draft of the proposed Metabolism
Guideline revisions will be available from the public docket within a
week or two prior to the meeting.
Any member of the public wishing to submit written comments should
contact the OPP docket staff at the address or the phone number given
above. Interested persons are permitted to file written statements
before the meeting. To the extent that time permits and upon advance
notice, interested persons may be permitted to present oral statements
at the meeting. There is no limit on written comments for consideration
by the Panel, but oral statements before the Panel are limited to
approximately 5 minutes. Since oral statements will be permitted only
as time permits, the Agency urges the public to submit written comments
in lieu of oral presentations. Persons wishing to make oral and/or
written [[Page 21814]] statements should notify the OPP docket staff
and submit three copies of a summary no later than May 17, 1995, in
order to ensure appropriate consideration by the Panel.
A record has been established for this document under docket number
``OPP-00408'' (including comments and data submitted electronically as
described below). A public version of this record, including printed,
paper versions of electronic comments, which does not include any
information claimed as CBI, is available for inspection from 8 a.m. to
4:30 p.m., Monday through Friday, excluding legal holidays. The public
record is located in Rm. 1132 of the Public Response and Program
Resources Branch, Field Operations Division (7506C), Office of
Pesticide Programs, Environmental Protection Agency, Crystal Mall #2,
1921 Jefferson Davis Highway, Arlington, VA.
Electronic comments can be sent directly to EPA at:
opp-docket@epamail.epa.gov
Electronic comments must be submitted as an ASCII file avoiding the
use of special characters and any form of encryption.
The official record for this document, as well as the public
version, as described above will be kept in paper form. Accordingly,
EPA will transfer all comments received electronically into printed,
paper form as they are received and will place the paper copies in the
official record which will also include all comments submitted directly
in writing. The official record is the paper record maintained at the
address in ``ADDRESSES'' at the beginning of this document.
Information submitted as a comment in response to this notice may
be claimed confidential by marking any part or all of that information
as CBI. Information so marked will not be disclosed except in
accordance with procedures set forth in 40 CFR part 2. A copy of the
comment that does not contain CBI must be submitted for inclusion in
the public docket. Information not marked confidential will be included
in the public docket without prior notice. All statements will be made
part of the record and will be taken into consideration by the Panel.
'Dated: April 27, 1995.
Stephanie R. Irene,
Acting Director, Health Effects Division, Office of Pesticide Programs.
[FR Doc. 95-10865 Filed 5-2-95; 8:45 am]
BILLING CODE 6560-50-F
