97-16475. Hepatitis B Vaccination Evaluation Project in Vietnamese-American Children  

  • [Federal Register Volume 62, Number 121 (Tuesday, June 24, 1997)]
    [Notices]
    [Pages 34066-34070]
    From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
    [FR Doc No: 97-16475]
    
    
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    DEPARTMENT OF HEALTH AND HUMAN SERVICES
    
    Centers for Disease Control and Prevention
    [Announcement 772]
    
    
    Hepatitis B Vaccination Evaluation Project in Vietnamese-American 
    Children
    
    Introduction
    
        The Centers for Disease Control and Prevention (CDC) announces the 
    availability of funds in fiscal year (FY) 1997 for a cooperative 
    agreement program to evaluate feasible methods of providing hepatitis B 
    vaccine to children 3-16 years of age in the Vietnamese-American 
    population in the United States.
        CDC is committed to achieving the health promotion and disease 
    prevention objectives of Healthy People 2000, a national activity to 
    reduce morbidity and mortality and improve the quality of life. This 
    announcement is related to the priority area of Immunization and 
    Infectious Diseases. (For ordering a copy of Healthy People 2000, see 
    the Section Where to Obtain Additional Information.)
    
    Authority
    
        This program is authorized under section 317 [42 U.S.C. 247b], of 
    the Public Health Service Act, as amended.
    
    Smoke-Free Workplace
    
        CDC strongly encourages all grant recipients to provide a smoke-
    free workplace and promote the nonuse of all tobacco products, and 
    Public Law 103-227, the Pro-Children Act of 1994, prohibits smoking in 
    certain facilities that receive Federal funds in which education, 
    library, day care, health care, and early childhood development 
    services are provided to children.
    
    Eligible Applicants
    
        Applications may be submitted by public and private nonprofit 
    organizations and State governments and their agencies.
    
        Note: An organization described in section 501(c)(4) of the 
    Internal Revenue Code of 1986 which engages in lobbying activities 
    shall not be eligible to receive Federal funds constituting an 
    award, grant, contract, loan, or any other form.
    
        Eligible applicants may enter into contractual agreements, as 
    necessary, to meet the requirements of the program and to strengthen 
    the overall application. The intent to use such mechanisms must be 
    stated in the application and the nature and scope of work of these 
    mechanisms require the approval of CDC.
        Awardee(s) must maintain the primary responsibility for conduct of 
    the cooperative agreement. The awardee, as the direct and primary 
    recipient of Federal funds, must perform a substantive role in carrying 
    out project activities and not merely serve as a conduit for an award 
    to another party or provide funds to an ineligible party. Applicants 
    must justify the need to use a contractor. If contractors are proposed, 
    the following must be provided: (1) Name of the contractor, (2) method 
    of selection, (3) period of performance, (4) detailed budget, (5) 
    justification for use of contractor, and (6) assurance of non-conflict 
    of interest.
    
    Availability of Funds
    
        Approximately $220,000 will be available in FY 1997 (for both 
    direct and indirect costs) to fund one award. It is expected that the 
    award will begin on or about September 30, 1997, for a 12-month budget 
    period within a project period of up to 3 years. Funding estimates may 
    vary and are subject to change.
        Continuation awards within the project period will be made on the 
    basis of the following criteria:
    
    1. Satisfactory progress in meeting program objectives.
    2. Extent to which the continuation year objectives are realistic, 
    specific, and measurable.
    3. Extent to which proposed changes in program objectives, methods of 
    operation, staff or contractor(s), or evaluation procedures will 
    facilitate achievement of project goals.
    4. Extent to which budget changes or requests are clearly justified and 
    consistent with the intended use of cooperative agreement funds.
    5. The availability of funds.
    
    Use of Funds
    
    Restrictions on Lobbying
    
        Applicants should be aware of restrictions on the use of HHS funds 
    for lobbying of Federal or State legislative bodies. Under the 
    provisions of 31 U.S.C. Section 1352 (which has been in effect since 
    December 23, 1989), recipients (and their subtier contractors) are 
    prohibited from using appropriated Federal funds (other than profits 
    from a Federal contract) for lobbying Congress or any Federal agency in 
    connection with the award of a particular contract, grant, cooperative 
    agreement, or loan. This includes grants/cooperative agreements that, 
    in whole or in part, involve conferences for which Federal funds cannot 
    be used directly or indirectly to encourage participants to lobby or to 
    instruct participants on how to lobby.
        In addition, the FY 1997 HHS Appropriations Act, which became 
    effective October 1, 1996, expressly prohibits the use of 1997 
    appropriated funds for indirect or ``grass roots'' lobbying efforts 
    that are designed to support or defeat legislation pending before State 
    legislatures. This new law, Section 503 of Pub. L. No. 104-208, 
    provides as follows:
    
        Sec. 503(a) No part of any appropriation contained in this Act 
    shall be used, other than for normal and recognized executive-
    legislative relationships, for publicity or propaganda purposes, for 
    the preparation, distribution, or use of any kit, pamphlet, booklet, 
    publication, radio, television, or video presentation designed to 
    support or defeat legislation pending before the Congress, * * * 
    except in presentation to the Congress or any State legislative body 
    itself.
        (b) No part of any appropriation contained in this Act shall be 
    used to pay the salary or expenses of any grant or contract 
    recipient, or agent acting for such recipient, related to
    
    [[Page 34067]]
    
    any activity designed to influence legislation or appropriations 
    pending before the Congress or any State legislature.
    
        Department of Labor, Health and Human Services, and Education, and 
    Related Agencies Appropriations Act, 1997, as enacted by the Omnibus 
    Consolidated Appropriations Act, 1997, Division A, Title I, Section 
    101(e), Pub. L. No. 104-208 (September 30, 1996).
    
    Background
    
        Each year the hepatitis B virus (HBV) infects at least 150,000 
    individuals in the United States and about 5,000 people die of the 
    effects of chronic HBV infection. The risk of HBV infection and death 
    in the Vietnamese community within the U.S. is about 10 times greater 
    than for the remainder of the U.S. population. The full implementation 
    of routine infant hepatitis B vaccination will eventually eliminate HBV 
    transmission. However, a minimum of 20 years would be required to 
    completely vaccinate all children by vaccinating infants alone. With 
    the addition of recommendations for vaccination of adolescents by the 
    age 11-12 years, at the current projected rate of less than one birth 
    cohort per year, it will take at least 10 years to provide vaccine to 
    all children. HBV transmission to unvaccinated children could be 
    prevented by conducting ``catch-up'' hepatitis B vaccination programs 
    in the children of first generation immigrants from countries of high 
    or intermediate HBV endemicity. Vietnam is one of the countries with 
    the highest endemicity levels where life-time risks of HBV infection in 
    the unvaccinated approach 100 percent.
        Vietnamese are the fastest-growing Asian-Pacific Islander ethnic 
    group in the United States. Bureau of Census projections for 1997 
    indicate that there are 848,600 Vietnamese in the U.S. representing 8.4 
    percent of the total Asian and Pacific Islander American (APIA) 
    population and the largest South East Asian group in this country. 
    Large groups of Vietnamese live in major urban clusters throughout the 
    U.S., primarily in California, Texas, the metropolitan Washington, DC 
    area, Washington State and Louisiana. The community infrastructure in 
    these metropolitan areas is well established with Vietnamese specific 
    television, radio, and print media markets. More than 88 percent of 
    Vietnamese are foreign-born and 82 percent of those over 5 years of age 
    speak Vietnamese at home.
        The prevalence of chronic HBV infection is high among Vietnamese in 
    the U.S. Among those who arrived in the U.S. between 1984 and mid-1987, 
    the prevalence rate was 14.4 percent, 28.8 times the rate in the U.S. 
    general population (0.5 percent). Approximately one in seven Vietnamese 
    is a chronic HBV carrier. It can be anticipated that two out of every 
    hundred Vietnamese will die of hepatitis B-related liver disease.
        During 1995, demonstration projects in Philadelphia and San Diego 
    have found vaccination rates in Vietnamese children 3-13 years of age 
    of 4 percent and 15 percent, respectively. These demonstration projects 
    were designed to serve all of the APIA groups in several selected 
    communities that were predominantly South East Asian. The project staff 
    found that methods which worked well with one Asian ethnic group often 
    were not effective in another Asian ethnic group. Within 12 months, 
    hepatitis B vaccination completion levels for the combined Asian ethnic 
    groups, located in the targeted geographic areas, were raised to 20 
    percent and 30 percent, respectively. The findings of these projects 
    indicated that if it were possible, ethnic-group-specific health 
    education methods should be identified and implemented to improve 
    efficiency and effectiveness of hepatitis B vaccination catch-up 
    efforts.
        These projects identified the need for health education related to 
    hepatitis B in several areas. Among the key findings from these 
    projects were that a substantial proportion of the medical 
    professionals providing health care to the children of these 
    communities were unaware (1) of the ACIP recommendations to vaccinate 
    APIA 3-13 year old children with hepatitis B vaccine, (2) that the 
    Federal Vaccines for Children (VFC) program provided free hepatitis B 
    vaccine for these children (70 percent are eligible), and, (3) of the 
    magnitude of the risk for HBV infection and resulting death these APIA 
    children faced, compared to non-API children in the United States. 
    Also, the majority of parents of these children were not aware of the 
    HBV risks, the availability of a protective vaccine recommended for use 
    in APIA, or of the VFC Program. These findings show the need to provide 
    information to both the health professionals and the parents in these 
    communities.
        On February 28, 1997, CDC convened a special Task Force of medical 
    and public health professionals from around the country experienced in 
    providing hepatitis B vaccination to APIA to ensure that a specific 
    APIA vaccination goal will be attained. That goal is to raise hepatitis 
    B vaccination rates in APIA children born from 1984 through 1993 from 
    the current level of 10 percent to 90 percent by the close of the year 
    2000. The efforts outlined in this announcement will help achieve this 
    important goal.
        Hepatitis B virus transmission occurs at a higher rate in 
    Vietnamese families because HBV infection has been endemic in most 
    Asian populations for many centuries. Long before 1970 when the virus 
    was first discovered the lifetime risk for HBV infection in these 
    populations was almost 100 percent. From 10 percent to 20 percent of 
    the pregnant women were chronically infected and passed the virus on to 
    their infants at birth. Many of these infants became chronically 
    infected. Many children born to women who did not have HBV infection 
    were infected during childhood from exposure to other household members 
    with chronic HBV infections. Therefore since this virus is transmitted 
    by even small amounts of blood, transmission occurs easily within 
    families--hence the label a ``family disease.'' Where someone in the 
    family is chronically infected the other household members are very 
    likely to eventually be infected as well. These children are exposed in 
    the family and each successive generation was at higher risk than the 
    previous one until the vaccine was developed in the early 1980's and 
    now is being provided.
    
    Purpose
    
        The purpose of the hepatitis B vaccination education evaluation 
    project for Vietnamese children is to evaluate feasible methods of 
    ensuring hepatitis B vaccination of children 3-16 years of age in the 
    Vietnamese population within the United States, to create practical 
    methods for implementation nationwide, and to estimate hepatitis B 
    vaccination coverage rates in Vietnamese American children ages 3-16 
    years of age.
        The goals of this demonstration project are:
        1. To evaluate and compare the effectiveness (including cost-
    effectiveness) of two primarily different methods of ensuring hepatitis 
    B vaccination of Vietnamese children age 3-16 years by (1) conducting 
    baseline assessments of vaccination rates (coverage), (2) developing 
    and applying the interventions, and (3) measuring the effectiveness of 
    the interventions.
        2. To determine the factors that are most predictive of acceptance/
    completion of the 3-dose hepatitis B vaccination series and the 
    barriers associated with non-acceptance /non-completion in a defined 
    target group of Vietnamese children age 3-16 years.
        The project will: (1) Provide health education resulting in 
    hepatitis B
    
    [[Page 34068]]
    
    vaccination of 20,000 Vietnamese children in two of the largest 
    Vietnamese communities in the United States, (2) provide a template to 
    aid the national efforts to ensure hepatitis B vaccination for the 
    estimated 292,756 Vietnamese-American children, (3) add to the existing 
    knowledge about ``catch-up'' hepatitis B vaccination programs in 
    Vietnamese communities across the nation, and (4) accurately measure 
    hepatitis B vaccination coverage rates in children ages 3-16 years in 
    three of the largest Vietnamese communities in the United States in 
    1998 and again in the year 2000.
    
    Program Requirements
    
        In conducting activities to achieve the purpose of this project, 
    the recipient shall be responsible for the activities under A., below, 
    and CDC shall be responsible for conducting activities under B., below:
    
    A. Recipient Activities
    
        1. Develop and implement a research design that will evaluate the 
    effectiveness of two separate and specific intervention methods. Apply 
    methods, one each, in two separate Vietnamese communities with a third 
    community serving as a comparison. The hepatitis B vaccination efforts 
    in this third community should be comparable to those being conducted 
    around the country. However, except for the pre-and post intervention 
    telephone surveys conducted with a small random sample of parents, 
    there will not be any added efforts in this comparison community.
        a. Conduct pre- and post-test measures in these three communities.
        b. Develop a media-based intervention exclusively, utilizing 
    Vietnamese-language electronic, print and outdoor media.
        c. Utilize a community mobilization model which will include the 
    formation of a coalition of community leaders and agencies which will 
    conduct grass-roots, person-to-person community organizing activities.
        2. Promote the delivery of hepatitis B vaccine to all eligible 
    Vietnamese children age 2-16 within the two target study communities 
    through a network which may include public and private clinics, 
    hospitals, and private doctors offices; Women, Infants and Children 
    (WIC) and Aid to Families with Dependent Children (AFDC) sites as well 
    as in day care centers, pre-schools, and elementary and high school 
    based clinics; religious and community organizations; and through in-
    home visitation and mobile vans.
        3. Follow published, scientifically valid methods of sample size 
    and power calculations, sample selection, survey design, data 
    collection, data management and data analysis.
        4. After completing the design, pretest and review phases, conduct 
    a baseline household sample survey to measure hepatitis B vaccination 
    levels and knowledge, attitudes, behaviors, and barriers related to 
    hepatitis B vaccination.
        5. After conducting the baseline survey using the methods outlined 
    in 2. above:
        a. Provide the culturally appropriate education on the risks of HBV 
    infection and benefits of hepatitis B vaccination to all individuals in 
    the two target study groups; and
        b. Inform all individuals in the two target study groups of the 
    availability of free hepatitis B vaccinations for most 3-16 year old 
    Vietnamese children in the two target study groups.
        6. Make available the information materials developed/modified and/
    or evaluated during this project for use in similar populations 
    throughout the United States as indicated.
        7. Develop a final report and prepare a manuscript in for 
    submission to a peer reviewed journal for publication.
        8. Adhere to the detailed time-line provided by the recipient and 
    approved by CDC which includes each major step necessary to accomplish 
    the recipient activities listed above.
        9. Provide documentation of human subjects approval.
    
    B. CDC Activities
    
        1. Provide scientific assistance needed to produce or adapt the 
    educational materials to educate the community members.
        2. Provide technical assistance in regard to survey and other 
    assessment and evaluation activities, analysis, manuscript development 
    and other activities associated with the project.
        3. Coordinate meetings with recipients and representatives of other 
    education/community outreach and evaluation projects.
        4. Provide technical assistance in the development of protocols for 
    a community education and training program cooperatively with 
    recipients.
        5. Provide information regarding CDC research projects related to 
    hepatitis B vaccination in APIA communities.
        6. Collaborate with recipients on the use of media and coalition 
    methods for community health education.
    
    Technical Reporting Requirements
    
        Quarterly progress reports are required. An original and two copies 
    of each report will be due 30 days after the end of each quarter. 
    Submission due dates will be established at the time of the award. A 
    financial status report (FSR) is due 90 days after the end of each 
    budget period. An original and two copies of a final performance report 
    and FSR are due no later than 90 days after the end of the project 
    period.
        Progress reports and the final performance report must include the 
    following:
        1. Restate each objective and under each address the progress made 
    on each item listed under Program Requirements section in this 
    announcement as well as each specific additional activity included in 
    the recipient's accepted proposal.
        2. Under each objective list and explain any deviation from the 
    time-line presented and approved in the recipient's accepted proposal; 
    provide specific steps that are being or will be taken to return to the 
    original agreed upon time-line.
        3. Under each objective list and explain any problems that have 
    been encountered and the steps that have been or will be taken to 
    overcome these problems.
        4. Include frequency tabulations for the key items in the surveys 
    conducted during the reporting period.
        5. Succinctly describe and quantify presentations made during the 
    reporting period related to the project.
        6. Include, in the appendix, estimates of the number of vaccine 
    recipients by dose of hepatitis B vaccine administered.
        7. Include, in the appendix, copies of key correspondence regarding 
    the demonstration project.
        8. Include, in the appendix, copies of all informational materials 
    utilized in the community outreach components of this demonstration 
    project.
        9. Include, in the appendix, copies of all survey instruments used 
    or to be used in this demonstration project.
        10. Include any other activity or item felt by the project director 
    to be pertinent.
        All reports must be submitted to Ron Van Duyne, Grants Management 
    Officer, Attention: David Elswick, Grants Management Branch, 
    Procurement and Grants Office, Centers for Disease Control and 
    Prevention (CDC), 255 East Paces Ferry Road, NE., Room 300, Mailstop E-
    13, Atlanta, GA 30305.
    
    Application Content
    
        To assist in developing the application, applicants should use as 
    guidance the information provided below and in the Evaluation Criteria
    
    [[Page 34069]]
    
    section of the announcement. The application must:
        1. Demonstrate that the applicant has the following:
        a. The ability and opportunity to evaluate three populations of at 
    least 20,000 Vietnamese people each within a community or geographic 
    area that can be defined and approached with a television media based 
    immunization outreach program and which are similar on relevant 
    characteristics such as demographic, geographic, social economic 
    status, and health care profiles.
        b. Established links to the Vietnamese community with culturally 
    appropriate and sensitive outreach methods.
        c. A history of successful completion of telephone survey research 
    projects as part of medical or public health outreach programs within 
    the Vietnamese community.
        d. Prior experience in the development and evaluation of effective 
    perinatal and universal infant hepatitis B vaccination programs within 
    the Vietnamese population.
        e. Culturally appropriate, commercial quality, topic specific 
    video, audio, print, and outdoor media materials previously developed 
    and tested in Vietnamese communities.
        2. Include a complete and detailed proposal that will serve as the 
    plan and general protocol for the entire demonstration project. 
    Applicants should provide a title page; a table of contents; an 
    introduction section with goals and objectives; followed with a 
    background section including complete but brief descriptions of the 
    target populations and the current perinatal and routine infant 
    hepatitis B vaccination programs in the target population; a methods 
    section with educational methods, evaluation and analytic methods, 
    goals and objectives of each survey as well as list of variables to be 
    measured and questions to be answered by each survey; a detailed time-
    line including all major steps and events; an appendix with (1) 
    curricula vita of the managers and supervisors and principal 
    investigator(s) with job descriptions of jobs that will be filled by 
    the cooperative agreement monies; (2) a list of previous or ongoing 
    similar projects conducted in this or similar communities showing the 
    amount of funding, funding agencies, dates of the project, principal 
    investigator, and a brief summary of each project; and (3) original 
    letters of support including commitments to detailed activities with 
    the appropriate signatures from a minimum of three major community 
    groups working within the target population, the health care providers 
    serving at least 80 percent of the target population, and a minimum of 
    two school districts within the target population, as well as all 
    subcontractors to be hired for any portion of the project.
        3. Provide the names, qualifications, and time allocations of the 
    professional staff to be assigned to this project; the support staff 
    available for the performance of this project; and the facilities and 
    equipment available for performance of this project.
        4. If applicable, provide a description of any work that is to be 
    performed by a subcontractor for the applicant. Proposed contracts 
    should identify the name of the contractor, if known; describe the 
    services to be performed; provide an itemized budget and justification 
    for the estimated costs of the contract; specify the period of 
    performance and method of selection.
        5. Provide evidence of collaboration with various groups necessary 
    for the conduct of this project. These groups may include: community 
    organizations, health care providers, and public health professionals 
    from technical or academic centers with expertise in appropriate 
    fields.
        6. Demonstrate partnerships with local or regional institutions 
    that can assist in program implementation.
        7. The proposed budget should clearly indicate what proportion of 
    each staff member's time is to be allocated to the project.
        8. While there is no legislative mandate for matching funds, all 
    local matching resources should be shown with the proposed budget.
        9. Detailed budgets are not necessary for years two and three, but 
    operational objectives should be included for years two and three of 
    the project. Applicants should provide a detailed description of the 
    proposed first year activities. Completed budget forms should be placed 
    at the beginning of the application. Applicants should provide a 
    detailed budget, with accompanying justification of all costs, that is 
    consistent with the stated objectives and planned activities of the 
    project. CDC may not approve or fund all proposed activities. 
    Applicants should be precise about the program purpose of each budget 
    item.
        The application pages must be clearly numbered and a complete index 
    to the application and its appendices must be included. Each section of 
    the proposal should be on a new page. The original and each copy of the 
    application set must be submitted unstapled and unbound. All material 
    must be typewritten, double spaced, with un-reduced type on 8\1/2\'' by 
    11'' paper, with at least 1'' margins, and printed on one side only.
    
    Evaluation Criteria
    
        The application will be reviewed and evaluated according to the 
    following criteria:
        1. The extent to which the applicant's proposal: (a) Demonstrates 
    the applicant's understanding of the purpose of the project and the 
    feasibility of producing the required results; and (b) includes 
    background information and other data to demonstrate that the applicant 
    has the appropriate organizational structure, administrative support 
    and accessibility to an adequate number of participants in the target 
    populations to accomplish study objectives, including culturally 
    appropriate outreach activities. (20%)
        2. The degree to which the plan of operation covers the ``Program 
    Requirements'', is consistent with study goals and is realistic, 
    specific, measurable and time-phased, and specifies the what, who, 
    where, how and the timing for start and completion of each step. (20%)
        3. The degree to which the applicant's plan demonstrates the 
    scientific soundness of the research methods and survey instruments to 
    be used. (20%)
        4. The qualifications and commitment of the applicant; allocations 
    of time and effort of staff devoted to the project; and the 
    qualifications of the primary and support staff. (15%)
        5. The applicant's ability to collaborate with other agencies for 
    conduct of the project, including the degree of commitment and 
    cooperation of collaborating parties. (10%)
        6. The extent to which the applicant demonstrates a cultural 
    competency for the proposed education, training, and telephone 
    interviewing. (15%)
        7. The extent the proposed budget is reasonable, with a concise and 
    clear justification, and consistent with the intended use of 
    cooperative agreement funds. The application will also be reviewed as 
    to the adequacy of existing and proposed facilities and resources for 
    conducting project activities. (Not Scored)
        Site visits may be conducted before final funding decisions are 
    made by CDC. Only the organizations with high ranking applications will 
    be visited. During the visit, CDC staff will determine if all necessary 
    components for start-up of the project are in place. This meeting will 
    be conducted by the CDC representatives with participation by local 
    staff and others who may have interest in this project. Periodic site 
    visits will be held as indicated thereafter to monitor progress.
    
    [[Page 34070]]
    
    Executive Order 12372 Review
    
        Applications are subject to Intergovernmental Review of Federal 
    Programs as governed by Executive Order (E.O.) 12372. E.O. 12372 sets 
    up a system for State and local government review of proposed Federal 
    assistance applications. Applicants should contact their State Single 
    Point of Contact (SPOC) as early as possible to alert them to the 
    prospective applications and receive any necessary instructions on the 
    State process. For proposed projects serving more than one State, the 
    applicant is advised to contact the SPOC for each affected State. A 
    current list of SPOCs is included in the application kit. If SPOCs have 
    any State process recommendations on applications submitted to CDC, 
    they should send them to Ron Van Duyne, Grants Management Officer, 
    Grants Management Branch, Procurement and Grants Office, Centers for 
    Disease Control and Prevention (CDC), 255 East Paces Ferry Road, NE., 
    Room 300, Mailstop E-13, Atlanta, GA 30305, no later than 30 days after 
    the application deadline. The Announcement Number and Program Title 
    should be referenced on the document. The granting agency does not 
    guarantee to ``accommodate or explain'' the State process 
    recommendations it receives after that date.
    
    Public Health System Reporting Requirements
    
        This program is subject to the Public Health System Reporting 
    Requirements. Under these requirements, all community-based 
    nongovernmental applicants must prepare and submit the items identified 
    below to the head of the appropriate State and/or local health 
    agency(s) in the program area(s) that may be impacted by the proposed 
    project no later than the receipt date of the Federal application. The 
    appropriate State and/or local health agency is determined by the 
    applicant. The following information must be provided:
        1. A copy of the face page of the application (SF424).
        2. A summary of the project that should be titled ``Public Health 
    System Impact Statement'' (PHSIS), not to exceed one page, and include 
    the following:
        a. A description of the population to be served;
        b. A summary of the services to be provided; and
        c. A description of the coordination plans with the appropriate 
    State and/or local health agencies.
        If the State and/or local health official should desire a copy of 
    the entire application, it may be obtained from the State Single Point 
    of Contact (SPOC) or directly from the applicant.
    
    Catalog of Federal Domestic Assistance Number
    
        The Catalog of Federal Domestic Assistance Number is 93.283.
    
    Other Requirements
    
    Surveys
    
        To document timely preparation and allow for input from CDC prior 
    to implementation, DRAFTS of the pre-intervention baseline household 
    survey questionnaire should be sent to CDC within two months of the 
    initial notice of grant award date.
        A sampling plan for the household survey should be sent to CDC for 
    review and comment prior to implementation. A draft of this plan should 
    be sent in writing within one month of receipt of initial notice of 
    grant award.
    
    Human Subjects
    
        The proposed project involves research on human subjects, 
    therefore, applicants must comply with the Department of Health and 
    Human Services Regulations, 45 CFR part 46, regarding the protection of 
    human subjects. Assurance must be provided to demonstrate the project 
    will be subject to initial and continuing review by an appropriate 
    institutional review committee. The applicant will be responsible for 
    providing assurance in accordance with the appropriate guidelines and 
    form provided in the application kit.
    
    Application Submission and Deadline
    
        An original and two copies of the application PHS Form 5161-1 (OMB 
    Number 0937-0189) must be submitted to Ron Van Duyne, Grants Management 
    Officer, Attention: David Elswick, Grants Management Branch, 
    Procurement and Grants Office, Centers for Disease Control and 
    Prevention (CDC), 255 East Paces Ferry Road, NE., Room 300, Mailstop E-
    13, Atlanta, GA 30305, on or before August 25, 1997.
    
    1. Deadline
    
        The application shall be considered as meeting the deadline if it 
    is either:
        a. Received on or before the deadline date, or
        b. Sent on or before the deadline date and received in time for 
    submission to the objective review group. Applicant must request a 
    legibly dated U.S. Postal Service postmark or obtain a legibly dated 
    receipt from a commercial carrier or the U.S. Postal Service. Private 
    metered postmarks shall not be acceptable as proof of timely mailing.
    
    2. Late Applications
    
        Applications which do not meet the criteria in 1.a. or 1.b. above 
    are considered late applications. A late application will not be 
    considered and will be returned to the applicant.
    
    Where To Obtain Additional Information
    
        A complete program description, information on application 
    procedures, an application package, and business management technical 
    assistance may be obtained from David Elswick, Grants Management 
    Specialist, Grants Management Branch, Procurement and Grants Office, 
    Centers for Disease Control and Prevention (CDC), 255 East Paces Ferry 
    Road, NE., Room 300, Mailstop E-13, Atlanta, GA 30305, telephone (404) 
    842-6521, Internet address: DCE1@cdc.gov.
        Programmatic technical assistance may be obtained from Gary L. 
    Euler, DrPH, Chief, Hepatitis Activity, Adult Vaccine Preventable 
    Diseases Branch, Epidemiology and Surveillance Division, National 
    Immunization Program, Centers for Disease Control and Prevention (CDC), 
    1600 Clifton Road NE. Mailstop E-61, Atlanta, GA 30333, telephone (404) 
    639-8742, Internet address: GLE0@cdc.gov.
        Please refer to Announcement 772 when requesting information and 
    submitting an application.
        A copy of ``Healthy People 2000'' (Full Report; Stock No. 017-001-
    00474-0) or ``Healthy People 2000'' (Summary Report; Stock No. 017-001-
    00473-1) referenced in the Introduction may be obtained through the 
    Superintendent of Documents, Government Printing Office, Washington, DC 
    20402-9325, telephone (202) 512-1800.
    
        Dated: June 18, 1997.
    Joseph R. Carter,
    Acting Deputy Associate Director for Management and Operations, Centers 
    for Disease Control and Prevention (CDC).
    [FR Doc. 97-16475 Filed 6-23-97; 8:45 am]
    BILLING CODE 4163-18-P
    
    
    

Document Information

Published:
06/24/1997
Department:
Centers for Disease Control and Prevention
Entry Type:
Notice
Document Number:
97-16475
Pages:
34066-34070 (5 pages)
Docket Numbers:
Announcement 772
PDF File:
97-16475.pdf