2024-21962. Proposed Aggregate Production Quotas for Schedule I and II Controlled Substances and Assessment of Annual Needs for the List I Chemicals Ephedrine, Pseudoephedrine, and Phenylpropanolamine for 2025
Table 1 a —States/Territories That Responded to DEA's Data Request
State/territory 1. Alabama. 2. Alaska. 3. Arkansas. 4. Commonwealth of Northern Mariana Islands. 5. Connecticut. 6. Delaware. 7. District of Columbia. 8. Idaho. 9. Indiana. 10. Kansas. 11. Kentucky. 12. Louisiana. 13. Maryland. 14. Massachusetts. 15. Michigan. 16. Minnesota. 17. Mississippi. 18. Montana. 19. Nevada. 20. New Jersey. 21. New Mexico. 22. North Carolina. 23. Oklahoma. 24. Oregon. 25. Pennsylvania. 26. Puerto Rico. 27. South Carolina. 28. South Dakota. 29. Utah. 30. Vermont. 31. Virginia. 32. Washington. Pharmacies are required by state law to enter controlled substance dispensing data into the state's PDMP database, including the prescriber's name, registered address and DEA number; prescription information (such as drug name); dispensing date; dosage dispensed; pharmacy registered address; and patient name and address. DEA considers PDMP data to be an accurate representation of dispensing activities in states. DEA received data for the following red-flag metrics:
- The total number of patients who saw three or more prescribers in a 90-day period and were dispensed an opioid following each visit. For this metric, DEA requested and was provided the number of prescriptions for the five covered controlled substances dispensed to these patients, as a percentage of the total prescriptions dispensed for that particular covered controlled substance, as well as the corresponding quantity of the covered controlled substance dispensed. This metric (patients being prescribed covered controlled substances from three or more prescribers in a 90-day period) is used to identify potential doctor shopping, a common technique to obtain a high number of controlled substances, which may lead to abuse or diversion of controlled substances. DEA has long considered doctor shopping to be an indicator of potential diversion.[10]
- The number of patients that were dispensed prescriptions for each of the five covered controlled substances that exceeded 240 morphine milligram equivalents (MME) daily. States provided the raw number of such prescriptions dispensed, the number of prescriptions as a percentage of the total covered controlled substance prescriptions dispensed, and the corresponding quantity of the covered controlled substance dispensed. DEA believes that accounting for quantities in excess of 240 MME daily allows for consideration of oncology patients with legitimate medical needs for covered controlled substance prescriptions with high MME. Higher dosages place individuals at higher risk of overdose and death. Prescriptions involving dosages exceeding 240 MME daily may indicate diversion, such as illegal distribution of controlled substances or prescribing outside the usual course of professional practice.
- The number of patients that paid cash for covered controlled substance prescriptions, without submitting for insurance reimbursement.[11] States also provided the number of prescriptions paid entirely with cash as a percentage ( print page 78776) of the total prescriptions for the five covered controlled substances dispensed, as well as the corresponding quantity of the covered controlled substances dispensed. When investigating potential diversion, cash payments are one element considered in identifying prescriptions filled for nonmedical purposes. Unusually high percentages of cash payments made to a prescriber or pharmacy for controlled substances may indicate diversion.[12]
DEA received PDMP data from the states in a standardized format that allowed DEA to aggregate the data. The PDMP data sample represents a population of approximately 112.35 million people, which is approximately 34 percent of the U.S. population. DEA believes this sample is sufficient to derive a reasonable nationwide estimate.
While PDMP data is useful in estimating diversion, it is not conclusive. Further investigation would be required before concluding that any of the subject prescriptions were actually diverted. DEA continues to evaluate its methodologies in estimating diversion in an effort to set quotas more efficiently. State participation is crucial to accurate data analysis, and DEA anticipates working closely with states, as well as other federal and state entities, in future quota determinations.
To calculate a national diversion estimate for each of the covered controlled substances from the responses received from state PDMP Administrators, DEA relied upon the number of individuals who received a prescription for a covered controlled substance that met any of the three red-flag metrics for each of calendar years 2021-2023. Using the population of the states responding to DEA's request, DEA then calculated the percentage of the population issued a prescription with a red flag. Using this estimated percentage for 2021-2023, DEA analyzed trends in the data to predict the estimated percentage of patients who would be expected to be included in these red-flag metrics for 2025.
DEA also reviewed aggregate sales data for each of the covered controlled substances, which it extracted from IQVIA's National Sales Perspective.[13] IQVIA sales data was selected to help quantify diversion at the national level because it reflects the best national estimate for all prescriptions written and filled, including the total quantity available for diversion or misuse. DEA analyzed trends in IQVIA sales data from January 2021-April 2024, in order to predict the estimated national sales for 2025.
To estimate diversion for each of the covered controlled substances, DEA multiplied the forecasted percentage of patients likely to receive a prescription for a covered controlled substance that meet any of the three red-flag metrics in 2025 by the forecasted sales data from IQVIA for 2025. The resulting estimate of diversion from data submitted by state PDMP Administrators is summarized below in Table 1b. This data contributed to the final diversion estimate set forth in Table 3.
Table 1 b —Diversion Estimates for 2025 Based on State PDMP Data for Covered Controlled Substances From 2021-2023
Controlled substance (g) Fentanyl 26 Hydrocodone 90,396 Hydromorphone 699 Oxycodone 234,372 Oxymorphone 000 Consideration of Registrant Reported Diversion in the Legitimate Distribution Chain
DEA extracted data from its Theft Loss Report database and categorized it by each basic drug class. DEA calculated the estimated amount of diversion by multiplying the quantity of API in each finished dosage form by the total amount of units reported stolen or lost to estimate the metric weight in grams of the controlled substance being diverted. This estimate of diversion from the legitimate supply chain for each of the covered controlled substances is displayed in Table 2. This data contributed to the final diversion estimates set forth in Table 3.
Table 2—Diversion Estimates Based on Supply Chain Diversion Data for Covered Controlled Substances
Controlled substance (g) Fentanyl 73 Hydrocodone 12,528 Hydromorphone 481 Oxycodone 30,265 Oxymorphone 165 In accordance with 21 U.S.C. 826(i), DEA's estimate of diversion for the five controlled substances was calculated by combining the values in Tables 1b and 2.
Table 3—Total Estimates of Diversion for Covered Controlled Substances To Be Considered in the 2025 APQs
Controlled substance (g) Fentanyl 99 Hydrocodone 102,924 Hydromorphone 1,180 Oxycodone 264,637 Oxymorphone 165 Continuing Efforts To Anticipate and Prevent Drug Shortages
Beginning in the latter half of 2022, the DEA and FDA observed an increase in the number of drug shortages reported by manufacturers of schedule II stimulants including mixed-salt amphetamine products starting in April 2022 and lisdexamfetamine and methylphenidate starting in July 2023. As DEA and FDA stated in an open letter in 2023,[14] we remain committed to doing all we can to prevent stimulant drug shortages, limit their impact, and resolve them as quickly as possible.
In particular, DEA continues to seek additional information that will assist the agency to more accurately forecast export requirements, especially for those substances controlled domestically in schedule I or II that are not controlled internationally. DEA understands that manufacturers have contractual obligations that dictate business decisions regarding the quantities of finished dosage forms they will produce under a single DEA-issued quota, which applies to products manufactured with an active ingredient, whether for domestic or foreign markets. DEA has purchased third-party data to improve its understanding of the dynamic changes in foreign markets. In February 2024, DEA began utilizing IQVIA's foreign (non-U.S.) sales tracking ( print page 78777) data module, MIDAS (Multi International Data Analysis System), which provides valuable insight into the growing export markets for schedule II stimulants. Building off the recently issued quota management rule,[15] DEA also intends to add new subcategories to individual manufacturing quotas and procurement quotas, to distinguish between domestic requirements and export requirements.
As part of DEA's continuing effort to prevent shortages and be more nimble in its administration of the quota program, DEA intends to continue to allocate procurement quotas to DEA-registered manufacturers of schedule II controlled substances on a semi-annual basis for the 2025 quota year, except that it will continue to allocate procurement quotas relating to injectable drug products containing schedule II controlled substances on an annual basis. DEA announced this change in a letter to DEA-registered manufacturers on April 29, 2024. No further change is being implemented at this time. DEA remains committed to ensuring that all patients with legitimate medical need can access appropriately prescribed medications.
The Administrator, therefore, proposes to establish the 2025 APQ for certain schedule I and II controlled substances and AAN for the list I chemicals ephedrine, pseudoephedrine, and phenylpropanolamine, expressed in grams of anhydrous acid or base, as follows:
Basic class Proposed 2025 quotas (g) Schedule I -[1-(2-Thienyl)cyclohexyl]pyrrolidine 20 1-(1-Phenylcyclohexyl)pyrrolidine 30 1-(2-Phenylethyl)-4-phenyl-4-acetoxypiperidine 10 1-(5-Fluoropentyl)-3-(1-naphthoyl)indole (AM2201) 30 1-(5-Fluoropentyl)-3-(2-iodobenzoyl)indole (AM694) 30 1-[1-(2-Thienyl)cyclohexyl]piperidine 15 2′-fluoro 2-fluorofentanyl 30 1-Benzylpiperazine 25 1-Methyl-4-phenyl-4-propionoxypiperidine 10 2-(2,5-Dimethoxy-4-ethylphenyl)ethanamine (2C-E) 30 2-(2,5-Dimethoxy-4-methylphenyl)ethanamine (2C-D) 30 2-(2,5-Dimethoxy-4-nitro-phenyl)ethanamine (2C-N) 30 2-(2,5-Dimethoxy-4-n-propylphenyl)ethanamine (2C-P) 30 2-(2,5-Dimethoxyphenyl)ethanamine (2C-H) 100 2-(4-Bromo-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine (25B-NBOMe; 2C-B-NBOMe; 25B; Cimbi-36) 30 2-(4-Chloro-2,5-dimethoxyphenyl)ethanamine (2C-C) 30 2-(4-Chloro-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine (25C-NBOMe; 2C-C-NBOMe; 25C; Cimbi-82) 25 2-(4-Iodo-2,5-dimethoxyphenyl)ethanamine (2C-I) 30 2-(4-Iodo-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine (25I-NBOMe; 2C-I-NBOMe; 25I; Cimbi-5) 30 2,5-Dimethoxy-4-ethylamphetamine (DOET) 25 2,5-Dimethoxy-4-n-propylthiophenethylamine 25 2,5-Dimethoxyamphetamine 25 2-[4-(Ethylthio)-2,5-dimethoxyphenyl]ethanamine (2C-T-2) 30 2-[4-(Isopropylthio)-2,5-dimethoxyphenyl]ethanamine (2C-T-4) 30 3,4,5-Trimethoxyamphetamine 30 2-Methyl AP-237 30 3,4-Methylenedioxyamphetamine (MDA) 12,000 3,4-Methylenedioxymethamphetamine (MDMA) 12,000 3,4-Methylenedioxy-N-ethylamphetamine (MDEA) 40 3,4-Methylenedioxy-N-methylcathinone (methylone) 5,200 3,4-Methylenedioxypyrovalerone (MDPV) 35 3-FMC; 3-Fluoro-N-methylcathinone 25 3-Methylfentanyl 30 3-Methylmethcathinone 30 3-Methylthiofentanyl 30 4,4′-Dimethylaminorex 30 4-Bromo-2,5-dimethoxyamphetamine (DOB) 30 4-Bromo-2,5-dimethoxyphenethylamine (2-CB) 5,100 4-Chloro-alpha-pyrrolidinovalerophenone (4-chloro-alpha-PVP) 25 4-CN-Cumyl-Butinaca 25 4-Fluoroisobutyryl fentanyl 30 4F-MDMB-BINACA 30 4-FMC; Flephedrone 25 4-MEC; 4-Methyl-N-ethylcathinone 25 4-Methoxyamphetamine 150 4-methyl-1-phenyl-2-(pyrrolidin-1-yl)pentan-1-one (alpha-PiHP) 30 4-Methyl-2,5-dimethoxyamphetamine (DOM) 25 4-Methylaminorex 25 4-Methyl-N-methylcathinone (mephedrone) 45 4-Methyl-alpha-ethylaminopentiophenone (4-MEAP) 25 4-Methyl-alpha-pyrrolidinohexiophenone (MPHP) 25 ( print page 78778) 4′-Methyl acetyl fentanyl 30 4-Methyl-α-pyrrolidinopropiophenone (4-MePPP) 25 4F-MDMB-BUTICA 30 5-(1,1-Dimethylheptyl)-2-[(1R,3S)-3-hydroxycyclohexyl]-phenol 50 5-(1,1-Dimethyloctyl)-2-[(1R,3S)-3-hydroxycyclohexyl]-phenol (cannabicyclohexanol or CP-47,497 C8-homolog) 40 5F-AB-PINACA; (1-Amino-3-methyl-1-oxobutan-2-yl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide 25 5F-ADB; 5F-MDMB-PINACA (methyl 2-(1-(5-fluoropentyl)-1H-indazole-3-carboxamido)-3,3-dimethylbutanoate) 25 5F-CUMYL-P7AICA; 1-(5-Fluoropentyl)-N-(2-phenylpropan-2-yl)-1H-pyrrolo[2,3-b]pyridine-3carboximide 25 5F-CUMYL-PINACA 25 5F-EDMB-PICA 30 5F-EDMB-PINACA 25 5F-MDMB-PICA 25 5F-AMB (methyl 2-(1-(5-fluoropentyl)-1H-indazole-3-carboxamido)-3-methylbutanoate) 25 5F-APINACA; 5F-AKB48 (N-(adamantan-1-yl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide) 25 5-Fluoro-PB-22; 5F-PB-22 25 5-Fluoro-UR144, XLR11 ([1-(5-fluoro-pentyl)-1Hindol-3-yl](2,2,3,3-tetramethylcyclopropyl)methanone 25 5-Methoxy-3,4-methylenedioxyamphetamine 25 5-Methoxy-N,N-diisopropyltryptamine 25 5-Methoxy-N,N-dimethyltryptamine 11,000 AB-CHMINACA 30 AB-FUBINACA 50 AB-PINACA 30 ADB-BUTINACA 30 ADB-FUBINACA (N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(4-fluorobenzyl)-1H-indazole-3-carboxamide) 30 Acetorphine 25 Acetyl Fentanyl 100 Acetyl-alpha-methylfentanyl 30 Acetyldihydrocodeine 30 Acetylmethadol 25 Acryl Fentanyl 25 ADB-4en-PINACA 30 ADB-PINACA (N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-pentyl-1H-indazole-3-carboxamide) 50 AH-7921 30 All other tetrahydrocannabinol 1,166,130 Allylprodine 25 Alphacetylmethadol 25 alpha-Ethyltryptamine 25 Alphameprodine 25 Alphamethadol 25 alpha-Methylfentanyl 30 alpha-Methylthiofentanyl 30 alpha-Methyltryptamine (AMT) 25 alpha-Pyrrolidinobutiophenone (α-PBP) 25 alpha-pyrrolidinoheptaphenone (PV8) 25 alpha-pyrrolidinohexabophenone (alpha-PHP) 25 alpha-Pyrrolidinopentiophenone (α-PVP) 25 Amineptine 30 Aminorex 25 Anileridine 20 APINCA, AKB48 (N-(1-adamantyl)-1-pentyl-1H-indazole-3-carboxamide) 25 Benzethidine 25 Benzylmorphine 30 Betacetylmethadol 25 beta-Hydroxy-3-methylfentanyl 30 beta-Hydroxyfentanyl 30 beta-Hydroxythiofentanyl 30 beta-Methyl fentanyl 30 beta′-Phenyl fentanyl 30 Betameprodine 25 Betamethadol 4 Betaprodine 25 Brorphine 30 Bufotenine 15 Butonitazene 30 Butylone 25 Butyryl fentanyl 30 Cathinone 40 Clonazolam 30 Clonitazene 25 Codeine methylbromide 30 Codeine-N-oxide 192 Crotonyl Fentanyl 25 ( print page 78779) CUMYL-PEGACLONE 30 Cyclopentyl Fentanyl 30 Cyclopropyl Fentanyl 20 Cyprenorphine 25 d-9-THC 1,523,040 Desomorphine 25 Dextromoramide 25 Diapromide 20 Diclazepam 30 Diethylthiambutene 20 Diethyltryptamine 25 Difenoxin 9,300 Dihydromorphine 639,954 Dimenoxadol 25 Dimepheptanol 25 Dimethylthiambutene 20 Dimethyltryptamine 11,000 Dioxyaphetyl butyrate 25 Dipipanone 25 Drotebanol 25 Ethylmethylthiambutene 25 Ethylone 25 Etizolam 30 Etodesnitazene 30 Etonitazene 25 Etorphine 30 Etoxeridine 25 Eutylone 30 Fenethylline 30 Fentanyl carbamate 30 Fentanyl related substances 600 Flualprazolam 30 Flubromazolam 30 Flunitazene 30 FUB-144 25 FUB-AKB48 25 Fub-AMB, MMB-Fubinaca, AMB-Fubinaca 25 Furanyl fentanyl 30 Furethidine 25 gamma-Hydroxybutyric acid 49,675,266 Heroin 150 Hydromorphinol 40 Hydroxypethidine 25 Ibogaine 210 Isobutyryl Fentanyl 25 Isotonitazine 25 JWH-018 and AM678 (1-Pentyl-3-(1-naphthoyl)indole) 35 JWH-019 (1-Hexyl-3-(1-naphthoyl)indole) 45 JWH-073 (1-Butyl-3-(1-naphthoyl)indole) 45 JWH-081 (1-Pentyl-3-[1-(4-methoxynaphthoyl)]indole) 30 JWH-122 (1-Pentyl-3-(4-methyl-1-naphthoyl)indole) 30 JWH-200 (1-[2-(4-Morpholinyl)ethyl]-3-(1-naphthoyl)indole) 35 JWH-203 (1-Pentyl-3-(2-chlorophenylacetyl)indole) 30 JWH-250 (1-Pentyl-3-(2-methoxyphenylacetyl)indole) 30 JWH-398 (1-Pentyl-3-(4-chloro-1-naphthoyl)indole) 30 Ketobemidone 30 Levomoramide 25 Levophenyacylmorphan 25 Lysergic acid diethylamide (LSD) 1,200 MAB-CHMINACA; ADB-CHMINACA (N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(cyclohexylmethyl)-1H-indazole-3-carboxamide) 30 MDMB-CHMICA; MMB-CHMINACA(methyl 2-(1-(cyclohexylmethyl)-1H-indole-3-carboxamido)-3,3-dimethylbutanoate) 30 MDMB-FUBINACA (methyl 2-(1-(4-fluorobenzyl)-1H-indazole-3-carboxamido)-3,3-dimethylbutanoate) 30 MMB-CHMICA-(AMB-CHIMCA); Methyl-2-(1-(cyclohexylmethyl)-1H-indole-3-carboxamido)-3-methylbutanoate 25 Marijuana 6,675,000 Marijuana extract 1,000,000 MDMB-4en-PINACA 30 MMB-FUBICA 30 Mecloqualone 30 Mescaline 1,200 Mesocarb 30 Methaqualone 60 ( print page 78780) Methcathinone 25 Methiopropamine 30 Methoxetamine 30 Methoxyacetyl fentanyl 30 Methyldesorphine 5 Methyldihydromorphine 25 Metodesnitazene 30 Metonitazene 30 Morpheridine 25 Morphine methylbromide 5 Morphine methylsulfonate 5 Morphine-N-oxide 150 MT-45 30 Myrophine 25 NM2201: Naphthalen-1-yl 1-(5-fluorpentyl)-1H-indole-3-carboxylate 25 N,N-Dimethylamphetamine 25 Naphyrone 25 N-Desethyl isotonitazene 30 N-Ethyl-1-phenylcyclohexylamine 25 N-Ethyl-3-piperidyl benzilate 10 N-Ethylamphetamine 24 N-Ethylhexedrone 25 N-Ethylpentylone, ephylone 30 N-Hydroxy-3,4-methylenedioxyamphetamine 24 Nicocodeine 25 Nicomorphine 25 N-methyl-3-piperidyl benzilate 30 N-piperidinyl etonitazene 30 N-Pyrrolidino Etonitazene 30 Noracymethadol 25 Norlevorphanol 2,550 Normethadone 25 Normorphine 40 Norpipanone 25 Ocfentanil 25 ortho-Fluoroacryl fentanyl 30 ortho-Fluorobutyryl fentanyl 30 Ortho-Fluorofentanyl,2-Fluorofentanyl 30 ortho-Fluoroisobutyryl fentanyl 30 ortho-Methyl acetylfentanyl 30 ortho-Methyl methoxyacetyl fentanyl 30 Para-Chlorisobutyrl fentanyl 30 Para-flourobutyryl fentanyl 25 Para-fluorofentanyl 25 para-Fluoro furanyl fentanyl 30 Para-Methoxybutyrl fentanyl 30 Para-methoxymethamphetamine 30 para-Methylfentanyl 30 Parahexyl 5 PB-22; QUPIC 20 Pentedrone 25 Pentylone 25 Phenadoxone 25 Phenampromide 25 Phenomorphan 25 Phenoperidine 25 Phenyl fentanyl 30 Pholcodine 5 Piritramide 25 Proheptazine 25 Properidine 25 Propiram 25 Protonitazene 30 Psilocybin 30,000 Psilocin 36,000 Racemoramide 25 SR-18 and RCS-8 (1-Cyclohexylethyl-3-(2-methoxyphenylacetyl)indole) 45 SR-19 and RCS-4 (1-Pentyl-3-[(4-methoxy)-benzoyl]indole) 30 Tetrahydrofuranyl fentanyl 15 Thebacon 25 Thiafentanil 25 Thiofentanyl 25 ( print page 78781) Thiofuranyl fentanyl 30 THJ-2201 ( [1-(5-fluoropentyl)-1H-indazol-3-yl](naphthalen-1-yl)methanone) 30 Tilidine 25 Trimeperidine 25 UR-144 (1-pentyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone 25 U-47700 30 Valeryl fentanyl 25 Zipeprol 30 Schedule II 1-Phenylcyclohexylamine 15 1-Piperidinocyclohexanecarbonitrile 25 4-Anilino-N-phenethyl-4-piperidine (ANPP) 937,874 Alfentanil 5,000 Alphaprodine 25 Amobarbital 20,100 Bezitramide 25 Carfentanil 20 Cocaine 60,492 Codeine (for conversion) 942,452 Codeine (for sale) 19,262,957 d-amphetamine (for sale) 21,200,000 d,l-amphetamine 21,200,000 d-amphetamine (for conversion) 23,688,235 Dexmethylphenidate (for sale) 6,200,000 Dexmethylphenidate (for conversion) 5,374,683 Dextropropoxyphene 35 Dihydrocodeine 115,227 Dihydroetorphine 25 Diphenoxylate (for conversion) 14,100 Diphenoxylate (for sale) 770,800 Ecgonine 60,492 Ethylmorphine 30 Etorphine hydrochloride 32 Fentanyl 731,341 Glutethimide 25 Hydrocodone (for conversion) 1,250 Hydrocodone (for sale) 27,121,498 Hydromorphone 1,951,508 Isomethadone 30 L-amphetamine 30 Levo-alphacetylmethadol (LAAM) 25 Levomethorphan 30 Levorphanol 20,000 Lisdexamfetamine 32,736,000 Meperidine 681,184 Meperidine Intermediate-A 30 Meperidine Intermediate-B 30 Meperidine Intermediate-C 30 Metazocine 15 Methadone (for sale) 25,619,700 Methadone Intermediate 27,673,600 d,l-Methamphetamine 150 d-methamphetamine (for conversion) 485,020 d-methamphetamine (for sale) 47,000 l-methamphetamine 587,229 Methylphenidate (for sale) 53,283,000 Methylphenidate (for conversion) 19,975,468 Metopon 25 Moramide-intermediate 25 Morphine (for conversion) 2,393,200 Morphine (for sale) 20,805,957 Nabilone 62,000 Norfentanyl 25 Noroxymorphone (for conversion) 24,756,979 Noroxymorphone (for sale) 1,000 Oliceridine 25,100 Opium (powder) 250,000 Opium (tincture) 530,837 Oripavine 37,721,950 Oxycodone (for conversion) 437,827 ( print page 78782) Oxycodone (for sale) 53,584,449 Oxymorphone (for conversion) 31,773,105 Oxymorphone (for sale) 464,464 Pentobarbital 40,000,000 Phenazocine 25 Phencyclidine 35 Phenmetrazine 25 Phenylacetone 100 Piminodine 25 Racemethorphan 5 Racemorphan 5 Remifentanil 3,000 Secobarbital 172,100 Sufentanil 4,000 Tapentadol 10,390,226 Thebaine 57,137,944 List I Chemicals Ephedrine (for conversion) 41,100 Ephedrine (for sale) 3,933,336 Phenylpropanolamine (for conversion) 14,878,320 Phenylpropanolamine (for sale) 7,990,000 Pseudoephedrine (for conversion) 1,000 Pseudoephedrine (for sale) 186,617,466
Document Information
- Published:
- 09/25/2024
- Department:
- Drug Enforcement Administration
- Entry Type:
- Notice
- Action:
- Notice with request for comments.
- Document Number:
- 2024-21962
- Dates:
- Interested persons may file written comments on this notice in accordance with 21 CFR 1303.11(c) and 1315.11(d). Electronic comments must be submitted, and written comments must be postmarked, on or before October 25, 2024. Commenters should be aware that the electronic Federal Docket Management System will not accept comments after 11:59 p.m. Eastern Time on the last day of the comment period.
- Pages:
- 78772-78782 (11 pages)
- Docket Numbers:
- Docket No. DEA-1413P
- PDF File:
- 2024-21962.pdf