2024-21962. Proposed Aggregate Production Quotas for Schedule I and II Controlled Substances and Assessment of Annual Needs for the List I Chemicals Ephedrine, Pseudoephedrine, and Phenylpropanolamine for 2025  

  • Table 1 a —States/Territories That Responded to DEA's Data Request

    State/territory
    1. Alabama.
    2. Alaska.
    3. Arkansas.
    4. Commonwealth of Northern Mariana Islands.
    5. Connecticut.
    6. Delaware.
    7. District of Columbia.
    8. Idaho.
    9. Indiana.
    10. Kansas.
    11. Kentucky.
    12. Louisiana.
    13. Maryland.
    14. Massachusetts.
    15. Michigan.
    16. Minnesota.
    17. Mississippi.
    18. Montana.
    19. Nevada.
    20. New Jersey.
    21. New Mexico.
    22. North Carolina.
    23. Oklahoma.
    24. Oregon.
    25. Pennsylvania.
    26. Puerto Rico.
    27. South Carolina.
    28. South Dakota.
    29. Utah.
    30. Vermont.
    31. Virginia.
    32. Washington.

    Pharmacies are required by state law to enter controlled substance dispensing data into the state's PDMP database, including the prescriber's name, registered address and DEA number; prescription information (such as drug name); dispensing date; dosage dispensed; pharmacy registered address; and patient name and address. DEA considers PDMP data to be an accurate representation of dispensing activities in states. DEA received data for the following red-flag metrics:

    • The total number of patients who saw three or more prescribers in a 90-day period and were dispensed an opioid following each visit. For this metric, DEA requested and was provided the number of prescriptions for the five covered controlled substances dispensed to these patients, as a percentage of the total prescriptions dispensed for that particular covered controlled substance, as well as the corresponding quantity of the covered controlled substance dispensed. This metric (patients being prescribed covered controlled substances from three or more prescribers in a 90-day period) is used to identify potential doctor shopping, a common technique to obtain a high number of controlled substances, which may lead to abuse or diversion of controlled substances. DEA has long considered doctor shopping to be an indicator of potential diversion.[10]
    • The number of patients that were dispensed prescriptions for each of the five covered controlled substances that exceeded 240 morphine milligram equivalents (MME) daily. States provided the raw number of such prescriptions dispensed, the number of prescriptions as a percentage of the total covered controlled substance prescriptions dispensed, and the corresponding quantity of the covered controlled substance dispensed. DEA believes that accounting for quantities in excess of 240 MME daily allows for consideration of oncology patients with legitimate medical needs for covered controlled substance prescriptions with high MME. Higher dosages place individuals at higher risk of overdose and death. Prescriptions involving dosages exceeding 240 MME daily may indicate diversion, such as illegal distribution of controlled substances or prescribing outside the usual course of professional practice.
    • The number of patients that paid cash for covered controlled substance prescriptions, without submitting for insurance reimbursement.[11] States also provided the number of prescriptions paid entirely with cash as a percentage ( print page 78776) of the total prescriptions for the five covered controlled substances dispensed, as well as the corresponding quantity of the covered controlled substances dispensed. When investigating potential diversion, cash payments are one element considered in identifying prescriptions filled for nonmedical purposes. Unusually high percentages of cash payments made to a prescriber or pharmacy for controlled substances may indicate diversion.[12]

    DEA received PDMP data from the states in a standardized format that allowed DEA to aggregate the data. The PDMP data sample represents a population of approximately 112.35 million people, which is approximately 34 percent of the U.S. population. DEA believes this sample is sufficient to derive a reasonable nationwide estimate.

    While PDMP data is useful in estimating diversion, it is not conclusive. Further investigation would be required before concluding that any of the subject prescriptions were actually diverted. DEA continues to evaluate its methodologies in estimating diversion in an effort to set quotas more efficiently. State participation is crucial to accurate data analysis, and DEA anticipates working closely with states, as well as other federal and state entities, in future quota determinations.

    To calculate a national diversion estimate for each of the covered controlled substances from the responses received from state PDMP Administrators, DEA relied upon the number of individuals who received a prescription for a covered controlled substance that met any of the three red-flag metrics for each of calendar years 2021-2023. Using the population of the states responding to DEA's request, DEA then calculated the percentage of the population issued a prescription with a red flag. Using this estimated percentage for 2021-2023, DEA analyzed trends in the data to predict the estimated percentage of patients who would be expected to be included in these red-flag metrics for 2025.

    DEA also reviewed aggregate sales data for each of the covered controlled substances, which it extracted from IQVIA's National Sales Perspective.[13] IQVIA sales data was selected to help quantify diversion at the national level because it reflects the best national estimate for all prescriptions written and filled, including the total quantity available for diversion or misuse. DEA analyzed trends in IQVIA sales data from January 2021-April 2024, in order to predict the estimated national sales for 2025.

    To estimate diversion for each of the covered controlled substances, DEA multiplied the forecasted percentage of patients likely to receive a prescription for a covered controlled substance that meet any of the three red-flag metrics in 2025 by the forecasted sales data from IQVIA for 2025. The resulting estimate of diversion from data submitted by state PDMP Administrators is summarized below in Table 1b. This data contributed to the final diversion estimate set forth in Table 3.

    Table 1 b —Diversion Estimates for 2025 Based on State PDMP Data for Covered Controlled Substances From 2021-2023

    Controlled substance (g)
    Fentanyl 26
    Hydrocodone 90,396
    Hydromorphone 699
    Oxycodone 234,372
    Oxymorphone 000

    Consideration of Registrant Reported Diversion in the Legitimate Distribution Chain

    DEA extracted data from its Theft Loss Report database and categorized it by each basic drug class. DEA calculated the estimated amount of diversion by multiplying the quantity of API in each finished dosage form by the total amount of units reported stolen or lost to estimate the metric weight in grams of the controlled substance being diverted. This estimate of diversion from the legitimate supply chain for each of the covered controlled substances is displayed in Table 2. This data contributed to the final diversion estimates set forth in Table 3.

    Table 2—Diversion Estimates Based on Supply Chain Diversion Data for Covered Controlled Substances

    Controlled substance (g)
    Fentanyl 73
    Hydrocodone 12,528
    Hydromorphone 481
    Oxycodone 30,265
    Oxymorphone 165

    In accordance with 21 U.S.C. 826(i), DEA's estimate of diversion for the five controlled substances was calculated by combining the values in Tables 1b and 2.

    Table 3—Total Estimates of Diversion for Covered Controlled Substances To Be Considered in the 2025 APQs

    Controlled substance (g)
    Fentanyl 99
    Hydrocodone 102,924
    Hydromorphone 1,180
    Oxycodone 264,637
    Oxymorphone 165

    Continuing Efforts To Anticipate and Prevent Drug Shortages

    Beginning in the latter half of 2022, the DEA and FDA observed an increase in the number of drug shortages reported by manufacturers of schedule II stimulants including mixed-salt amphetamine products starting in April 2022 and lisdexamfetamine and methylphenidate starting in July 2023. As DEA and FDA stated in an open letter in 2023,[14] we remain committed to doing all we can to prevent stimulant drug shortages, limit their impact, and resolve them as quickly as possible.

    In particular, DEA continues to seek additional information that will assist the agency to more accurately forecast export requirements, especially for those substances controlled domestically in schedule I or II that are not controlled internationally. DEA understands that manufacturers have contractual obligations that dictate business decisions regarding the quantities of finished dosage forms they will produce under a single DEA-issued quota, which applies to products manufactured with an active ingredient, whether for domestic or foreign markets. DEA has purchased third-party data to improve its understanding of the dynamic changes in foreign markets. In February 2024, DEA began utilizing IQVIA's foreign (non-U.S.) sales tracking ( print page 78777) data module, MIDAS (Multi International Data Analysis System), which provides valuable insight into the growing export markets for schedule II stimulants. Building off the recently issued quota management rule,[15] DEA also intends to add new subcategories to individual manufacturing quotas and procurement quotas, to distinguish between domestic requirements and export requirements.

    As part of DEA's continuing effort to prevent shortages and be more nimble in its administration of the quota program, DEA intends to continue to allocate procurement quotas to DEA-registered manufacturers of schedule II controlled substances on a semi-annual basis for the 2025 quota year, except that it will continue to allocate procurement quotas relating to injectable drug products containing schedule II controlled substances on an annual basis. DEA announced this change in a letter to DEA-registered manufacturers on April 29, 2024. No further change is being implemented at this time. DEA remains committed to ensuring that all patients with legitimate medical need can access appropriately prescribed medications.

    The Administrator, therefore, proposes to establish the 2025 APQ for certain schedule I and II controlled substances and AAN for the list I chemicals ephedrine, pseudoephedrine, and phenylpropanolamine, expressed in grams of anhydrous acid or base, as follows:

    Basic class Proposed 2025 quotas (g)
    Schedule I
    -[1-(2-Thienyl)cyclohexyl]pyrrolidine 20
    1-(1-Phenylcyclohexyl)pyrrolidine 30
    1-(2-Phenylethyl)-4-phenyl-4-acetoxypiperidine 10
    1-(5-Fluoropentyl)-3-(1-naphthoyl)indole (AM2201) 30
    1-(5-Fluoropentyl)-3-(2-iodobenzoyl)indole (AM694) 30
    1-[1-(2-Thienyl)cyclohexyl]piperidine 15
    2′-fluoro 2-fluorofentanyl 30
    1-Benzylpiperazine 25
    1-Methyl-4-phenyl-4-propionoxypiperidine 10
    2-(2,5-Dimethoxy-4-ethylphenyl)ethanamine (2C-E) 30
    2-(2,5-Dimethoxy-4-methylphenyl)ethanamine (2C-D) 30
    2-(2,5-Dimethoxy-4-nitro-phenyl)ethanamine (2C-N) 30
    2-(2,5-Dimethoxy-4-n-propylphenyl)ethanamine (2C-P) 30
    2-(2,5-Dimethoxyphenyl)ethanamine (2C-H) 100
    2-(4-Bromo-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine (25B-NBOMe; 2C-B-NBOMe; 25B; Cimbi-36) 30
    2-(4-Chloro-2,5-dimethoxyphenyl)ethanamine (2C-C) 30
    2-(4-Chloro-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine (25C-NBOMe; 2C-C-NBOMe; 25C; Cimbi-82) 25
    2-(4-Iodo-2,5-dimethoxyphenyl)ethanamine (2C-I) 30
    2-(4-Iodo-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine (25I-NBOMe; 2C-I-NBOMe; 25I; Cimbi-5) 30
    2,5-Dimethoxy-4-ethylamphetamine (DOET) 25
    2,5-Dimethoxy-4-n-propylthiophenethylamine 25
    2,5-Dimethoxyamphetamine 25
    2-[4-(Ethylthio)-2,5-dimethoxyphenyl]ethanamine (2C-T-2) 30
    2-[4-(Isopropylthio)-2,5-dimethoxyphenyl]ethanamine (2C-T-4) 30
    3,4,5-Trimethoxyamphetamine 30
    2-Methyl AP-237 30
    3,4-Methylenedioxyamphetamine (MDA) 12,000
    3,4-Methylenedioxymethamphetamine (MDMA) 12,000
    3,4-Methylenedioxy-N-ethylamphetamine (MDEA) 40
    3,4-Methylenedioxy-N-methylcathinone (methylone) 5,200
    3,4-Methylenedioxypyrovalerone (MDPV) 35
    3-FMC; 3-Fluoro-N-methylcathinone 25
    3-Methylfentanyl 30
    3-Methylmethcathinone 30
    3-Methylthiofentanyl 30
    4,4′-Dimethylaminorex 30
    4-Bromo-2,5-dimethoxyamphetamine (DOB) 30
    4-Bromo-2,5-dimethoxyphenethylamine (2-CB) 5,100
    4-Chloro-alpha-pyrrolidinovalerophenone (4-chloro-alpha-PVP) 25
    4-CN-Cumyl-Butinaca 25
    4-Fluoroisobutyryl fentanyl 30
    4F-MDMB-BINACA 30
    4-FMC; Flephedrone 25
    4-MEC; 4-Methyl-N-ethylcathinone 25
    4-Methoxyamphetamine 150
    4-methyl-1-phenyl-2-(pyrrolidin-1-yl)pentan-1-one (alpha-PiHP) 30
    4-Methyl-2,5-dimethoxyamphetamine (DOM) 25
    4-Methylaminorex 25
    4-Methyl-N-methylcathinone (mephedrone) 45
    4-Methyl-alpha-ethylaminopentiophenone (4-MEAP) 25
    4-Methyl-alpha-pyrrolidinohexiophenone (MPHP) 25
    ( print page 78778)
    4′-Methyl acetyl fentanyl 30
    4-Methyl-α-pyrrolidinopropiophenone (4-MePPP) 25
    4F-MDMB-BUTICA 30
    5-(1,1-Dimethylheptyl)-2-[(1R,3S)-3-hydroxycyclohexyl]-phenol 50
    5-(1,1-Dimethyloctyl)-2-[(1R,3S)-3-hydroxycyclohexyl]-phenol (cannabicyclohexanol or CP-47,497 C8-homolog) 40
    5F-AB-PINACA; (1-Amino-3-methyl-1-oxobutan-2-yl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide 25
    5F-ADB; 5F-MDMB-PINACA (methyl 2-(1-(5-fluoropentyl)-1H-indazole-3-carboxamido)-3,3-dimethylbutanoate) 25
    5F-CUMYL-P7AICA; 1-(5-Fluoropentyl)-N-(2-phenylpropan-2-yl)-1H-pyrrolo[2,3-b]pyridine-3carboximide 25
    5F-CUMYL-PINACA 25
    5F-EDMB-PICA 30
    5F-EDMB-PINACA 25
    5F-MDMB-PICA 25
    5F-AMB (methyl 2-(1-(5-fluoropentyl)-1H-indazole-3-carboxamido)-3-methylbutanoate) 25
    5F-APINACA; 5F-AKB48 (N-(adamantan-1-yl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide) 25
    5-Fluoro-PB-22; 5F-PB-22 25
    5-Fluoro-UR144, XLR11 ([1-(5-fluoro-pentyl)-1Hindol-3-yl](2,2,3,3-tetramethylcyclopropyl)methanone 25
    5-Methoxy-3,4-methylenedioxyamphetamine 25
    5-Methoxy-N,N-diisopropyltryptamine 25
    5-Methoxy-N,N-dimethyltryptamine 11,000
    AB-CHMINACA 30
    AB-FUBINACA 50
    AB-PINACA 30
    ADB-BUTINACA 30
    ADB-FUBINACA (N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(4-fluorobenzyl)-1H-indazole-3-carboxamide) 30
    Acetorphine 25
    Acetyl Fentanyl 100
    Acetyl-alpha-methylfentanyl 30
    Acetyldihydrocodeine 30
    Acetylmethadol 25
    Acryl Fentanyl 25
    ADB-4en-PINACA 30
    ADB-PINACA (N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-pentyl-1H-indazole-3-carboxamide) 50
    AH-7921 30
    All other tetrahydrocannabinol 1,166,130
    Allylprodine 25
    Alphacetylmethadol 25
    alpha-Ethyltryptamine 25
    Alphameprodine 25
    Alphamethadol 25
    alpha-Methylfentanyl 30
    alpha-Methylthiofentanyl 30
    alpha-Methyltryptamine (AMT) 25
    alpha-Pyrrolidinobutiophenone (α-PBP) 25
    alpha-pyrrolidinoheptaphenone (PV8) 25
    alpha-pyrrolidinohexabophenone (alpha-PHP) 25
    alpha-Pyrrolidinopentiophenone (α-PVP) 25
    Amineptine 30
    Aminorex 25
    Anileridine 20
    APINCA, AKB48 (N-(1-adamantyl)-1-pentyl-1H-indazole-3-carboxamide) 25
    Benzethidine 25
    Benzylmorphine 30
    Betacetylmethadol 25
    beta-Hydroxy-3-methylfentanyl 30
    beta-Hydroxyfentanyl 30
    beta-Hydroxythiofentanyl 30
    beta-Methyl fentanyl 30
    beta′-Phenyl fentanyl 30
    Betameprodine 25
    Betamethadol 4
    Betaprodine 25
    Brorphine 30
    Bufotenine 15
    Butonitazene 30
    Butylone 25
    Butyryl fentanyl 30
    Cathinone 40
    Clonazolam 30
    Clonitazene 25
    Codeine methylbromide 30
    Codeine-N-oxide 192
    Crotonyl Fentanyl 25
    ( print page 78779)
    CUMYL-PEGACLONE 30
    Cyclopentyl Fentanyl 30
    Cyclopropyl Fentanyl 20
    Cyprenorphine 25
    d-9-THC 1,523,040
    Desomorphine 25
    Dextromoramide 25
    Diapromide 20
    Diclazepam 30
    Diethylthiambutene 20
    Diethyltryptamine 25
    Difenoxin 9,300
    Dihydromorphine 639,954
    Dimenoxadol 25
    Dimepheptanol 25
    Dimethylthiambutene 20
    Dimethyltryptamine 11,000
    Dioxyaphetyl butyrate 25
    Dipipanone 25
    Drotebanol 25
    Ethylmethylthiambutene 25
    Ethylone 25
    Etizolam 30
    Etodesnitazene 30
    Etonitazene 25
    Etorphine 30
    Etoxeridine 25
    Eutylone 30
    Fenethylline 30
    Fentanyl carbamate 30
    Fentanyl related substances 600
    Flualprazolam 30
    Flubromazolam 30
    Flunitazene 30
    FUB-144 25
    FUB-AKB48 25
    Fub-AMB, MMB-Fubinaca, AMB-Fubinaca 25
    Furanyl fentanyl 30
    Furethidine 25
    gamma-Hydroxybutyric acid 49,675,266
    Heroin 150
    Hydromorphinol 40
    Hydroxypethidine 25
    Ibogaine 210
    Isobutyryl Fentanyl 25
    Isotonitazine 25
    JWH-018 and AM678 (1-Pentyl-3-(1-naphthoyl)indole) 35
    JWH-019 (1-Hexyl-3-(1-naphthoyl)indole) 45
    JWH-073 (1-Butyl-3-(1-naphthoyl)indole) 45
    JWH-081 (1-Pentyl-3-[1-(4-methoxynaphthoyl)]indole) 30
    JWH-122 (1-Pentyl-3-(4-methyl-1-naphthoyl)indole) 30
    JWH-200 (1-[2-(4-Morpholinyl)ethyl]-3-(1-naphthoyl)indole) 35
    JWH-203 (1-Pentyl-3-(2-chlorophenylacetyl)indole) 30
    JWH-250 (1-Pentyl-3-(2-methoxyphenylacetyl)indole) 30
    JWH-398 (1-Pentyl-3-(4-chloro-1-naphthoyl)indole) 30
    Ketobemidone 30
    Levomoramide 25
    Levophenyacylmorphan 25
    Lysergic acid diethylamide (LSD) 1,200
    MAB-CHMINACA; ADB-CHMINACA (N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(cyclohexylmethyl)-1H-indazole-3-carboxamide) 30
    MDMB-CHMICA; MMB-CHMINACA(methyl 2-(1-(cyclohexylmethyl)-1H-indole-3-carboxamido)-3,3-dimethylbutanoate) 30
    MDMB-FUBINACA (methyl 2-(1-(4-fluorobenzyl)-1H-indazole-3-carboxamido)-3,3-dimethylbutanoate) 30
    MMB-CHMICA-(AMB-CHIMCA); Methyl-2-(1-(cyclohexylmethyl)-1H-indole-3-carboxamido)-3-methylbutanoate 25
    Marijuana 6,675,000
    Marijuana extract 1,000,000
    MDMB-4en-PINACA 30
    MMB-FUBICA 30
    Mecloqualone 30
    Mescaline 1,200
    Mesocarb 30
    Methaqualone 60
    ( print page 78780)
    Methcathinone 25
    Methiopropamine 30
    Methoxetamine 30
    Methoxyacetyl fentanyl 30
    Methyldesorphine 5
    Methyldihydromorphine 25
    Metodesnitazene 30
    Metonitazene 30
    Morpheridine 25
    Morphine methylbromide 5
    Morphine methylsulfonate 5
    Morphine-N-oxide 150
    MT-45 30
    Myrophine 25
    NM2201: Naphthalen-1-yl 1-(5-fluorpentyl)-1H-indole-3-carboxylate 25
    N,N-Dimethylamphetamine 25
    Naphyrone 25
    N-Desethyl isotonitazene 30
    N-Ethyl-1-phenylcyclohexylamine 25
    N-Ethyl-3-piperidyl benzilate 10
    N-Ethylamphetamine 24
    N-Ethylhexedrone 25
    N-Ethylpentylone, ephylone 30
    N-Hydroxy-3,4-methylenedioxyamphetamine 24
    Nicocodeine 25
    Nicomorphine 25
    N-methyl-3-piperidyl benzilate 30
    N-piperidinyl etonitazene 30
    N-Pyrrolidino Etonitazene 30
    Noracymethadol 25
    Norlevorphanol 2,550
    Normethadone 25
    Normorphine 40
    Norpipanone 25
    Ocfentanil 25
    ortho-Fluoroacryl fentanyl 30
    ortho-Fluorobutyryl fentanyl 30
    Ortho-Fluorofentanyl,2-Fluorofentanyl 30
    ortho-Fluoroisobutyryl fentanyl 30
    ortho-Methyl acetylfentanyl 30
    ortho-Methyl methoxyacetyl fentanyl 30
    Para-Chlorisobutyrl fentanyl 30
    Para-flourobutyryl fentanyl 25
    Para-fluorofentanyl 25
    para-Fluoro furanyl fentanyl 30
    Para-Methoxybutyrl fentanyl 30
    Para-methoxymethamphetamine 30
    para-Methylfentanyl 30
    Parahexyl 5
    PB-22; QUPIC 20
    Pentedrone 25
    Pentylone 25
    Phenadoxone 25
    Phenampromide 25
    Phenomorphan 25
    Phenoperidine 25
    Phenyl fentanyl 30
    Pholcodine 5
    Piritramide 25
    Proheptazine 25
    Properidine 25
    Propiram 25
    Protonitazene 30
    Psilocybin 30,000
    Psilocin 36,000
    Racemoramide 25
    SR-18 and RCS-8 (1-Cyclohexylethyl-3-(2-methoxyphenylacetyl)indole) 45
    SR-19 and RCS-4 (1-Pentyl-3-[(4-methoxy)-benzoyl]indole) 30
    Tetrahydrofuranyl fentanyl 15
    Thebacon 25
    Thiafentanil 25
    Thiofentanyl 25
    ( print page 78781)
    Thiofuranyl fentanyl 30
    THJ-2201 ( [1-(5-fluoropentyl)-1H-indazol-3-yl](naphthalen-1-yl)methanone) 30
    Tilidine 25
    Trimeperidine 25
    UR-144 (1-pentyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone 25
    U-47700 30
    Valeryl fentanyl 25
    Zipeprol 30
    Schedule II
    1-Phenylcyclohexylamine 15
    1-Piperidinocyclohexanecarbonitrile 25
    4-Anilino-N-phenethyl-4-piperidine (ANPP) 937,874
    Alfentanil 5,000
    Alphaprodine 25
    Amobarbital 20,100
    Bezitramide 25
    Carfentanil 20
    Cocaine 60,492
    Codeine (for conversion) 942,452
    Codeine (for sale) 19,262,957
    d-amphetamine (for sale) 21,200,000
    d,l-amphetamine 21,200,000
    d-amphetamine (for conversion) 23,688,235
    Dexmethylphenidate (for sale) 6,200,000
    Dexmethylphenidate (for conversion) 5,374,683
    Dextropropoxyphene 35
    Dihydrocodeine 115,227
    Dihydroetorphine 25
    Diphenoxylate (for conversion) 14,100
    Diphenoxylate (for sale) 770,800
    Ecgonine 60,492
    Ethylmorphine 30
    Etorphine hydrochloride 32
    Fentanyl 731,341
    Glutethimide 25
    Hydrocodone (for conversion) 1,250
    Hydrocodone (for sale) 27,121,498
    Hydromorphone 1,951,508
    Isomethadone 30
    L-amphetamine 30
    Levo-alphacetylmethadol (LAAM) 25
    Levomethorphan 30
    Levorphanol 20,000
    Lisdexamfetamine 32,736,000
    Meperidine 681,184
    Meperidine Intermediate-A 30
    Meperidine Intermediate-B 30
    Meperidine Intermediate-C 30
    Metazocine 15
    Methadone (for sale) 25,619,700
    Methadone Intermediate 27,673,600
    d,l-Methamphetamine 150
    d-methamphetamine (for conversion) 485,020
    d-methamphetamine (for sale) 47,000
    l-methamphetamine 587,229
    Methylphenidate (for sale) 53,283,000
    Methylphenidate (for conversion) 19,975,468
    Metopon 25
    Moramide-intermediate 25
    Morphine (for conversion) 2,393,200
    Morphine (for sale) 20,805,957
    Nabilone 62,000
    Norfentanyl 25
    Noroxymorphone (for conversion) 24,756,979
    Noroxymorphone (for sale) 1,000
    Oliceridine 25,100
    Opium (powder) 250,000
    Opium (tincture) 530,837
    Oripavine 37,721,950
    Oxycodone (for conversion) 437,827
    ( print page 78782)
    Oxycodone (for sale) 53,584,449
    Oxymorphone (for conversion) 31,773,105
    Oxymorphone (for sale) 464,464
    Pentobarbital 40,000,000
    Phenazocine 25
    Phencyclidine 35
    Phenmetrazine 25
    Phenylacetone 100
    Piminodine 25
    Racemethorphan 5
    Racemorphan 5
    Remifentanil 3,000
    Secobarbital 172,100
    Sufentanil 4,000
    Tapentadol 10,390,226
    Thebaine 57,137,944
    List I Chemicals
    Ephedrine (for conversion) 41,100
    Ephedrine (for sale) 3,933,336
    Phenylpropanolamine (for conversion) 14,878,320
    Phenylpropanolamine (for sale) 7,990,000
    Pseudoephedrine (for conversion) 1,000
    Pseudoephedrine (for sale) 186,617,466

Document Information

Published:
09/25/2024
Department:
Drug Enforcement Administration
Entry Type:
Notice
Action:
Notice with request for comments.
Document Number:
2024-21962
Dates:
Interested persons may file written comments on this notice in accordance with 21 CFR 1303.11(c) and 1315.11(d). Electronic comments must be submitted, and written comments must be postmarked, on or before October 25, 2024. Commenters should be aware that the electronic Federal Docket Management System will not accept comments after 11:59 p.m. Eastern Time on the last day of the comment period.
Pages:
78772-78782 (11 pages)
Docket Numbers:
Docket No. DEA-1413P
PDF File:
2024-21962.pdf