01-18010. Availability for Non-Exclusive, Exclusive, or Partially Exclusive Licensing of U.S. Patent Application Concerning Immobilized Enzymes as Biosensors for Chemical Toxins

AGENCY:

U.S. Army Medical Research and Materiel Command, DoD.

ACTION:

Notice.

SUMMARY:

In accordance with 37 CFR 404.6, announcement is made of the availability for licensing of U.S. Patent Application No. 09/558,511 entitled “Immobilized Enzymes as Biosensors for Chemical Toxins” filed April 26, 2000. This patent has been assigned to the United States Government as represented by the Secretary of the Army.

ADDRESSES:

Commander, U.S. Army Medical Research and Materiel Command, ATTN: Command Judge Advocate, MCMR-JA, 504 Scott Street, Fort Detrick, Frederick, Maryland 21702-5012.

FOR FURTHER INFORMATION CONTACT:

For patent issues, Ms. Elizabeth Arwine, Patent Attorney, [phone]. For licensing issues, Dr. Paul Mele, Office of Research & Technology Assessment, [phone]. Both at telefax [phone].

SUPPLEMENTARY INFORMATION:

Methods, compositions and materials useful in the detection of organophosphorus and organosulfur compounds are disclosed. In particular. biosensors wherein a porous or a non-porous support having any enzyme immobilized upon or within are disclosed. The biosensors exhibit enzymatic stability at extreme temperatures and/or denaturing conditions, and similar kinetic characteristics of the soluble form of the enzymes utilized. The enzyme does not leach from the porous or non-porous support and the material retains enzymatic activity after prolonged storage. Differential biosensors are also disclosed.

Luz D. Ortiz,

Army Federal Register Liaison Officer.