We are proposing to amend the Virus-Serum-Toxin Act regulations concerning testing for avian lymphoid leukosis in veterinary biologics to specify that the test is for the detection of extraneous replicating avian leukosis virus; require such testing to be
conducted using a procedure that will detect extraneous replicating avian leukosis virus and that is acceptable to the Animal and Plant Health Inspection Service; require firms to develop a procedure to test for lymphoid leukosis virus contamination in the case of vaccine virus cytopathic to chick embryo cell cultures; and specify the equivalent
inoculum dose of vaccine to be used when testing certain specified chicken vaccines for lymphoid leukosis virus. These proposed changes would update the testing for lymphoid leukosis virus contamination by
prescribing a test procedure that increases the probability of detecting atypical lymphoid leukosis viruses such as those recently
found in a contaminated vaccine.
Document Subtype:
Proposed rule
Received Date:
January 31 2007, at 07:07 AM Eastern Standard Time
Start-End Page:
4467 - 4470
Comment Start Date:
January 31 2007, at 12:00 AM Eastern Standard Time
Viruses, Serums, Toxins, and Analogous Products; Detection of Avian Lymphoid Leukosis Virus
Details Information
Comments
Submitter: McClure, Kent Posted: 04/03/2007 ID: APHIS-2007-0001-0002
Apr 02,2007 11:59 PM ET
Related Documents