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Abstract: Quantitative dose-response evaluation of PON1 status: relevance at environmental concentrations. Age-dependent PBPK/PD modeling of preweanling rat: relevance to young children. Relevant charge questions…. Metabolism & Toxicokinetics Age-dependent sensitivity Cholinesterase Inhibition Juvenile rats more sensitive than adults Extrapolation/Uncertainty Factors PON-1 polymorphism
Document Subtype: Public Comment
Received Date: September 17 2008, at 04:36 PM Eastern Daylight Time
Page Count: 15

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Comment submitted by Charles Timchalk, Battelle Center for Biological Monitoring and Modeling

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